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Qing Yin Zheng, PhD
Associate ProfessorDepartment of OtolaryngologySchool of MedicineAssociate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineEmail: qing.zheng@case.edu
Phone: 216.844.3441
I research the genes and molecular pathways involved in mouse models of human deafness, including Otitis Media and Usher syndrome.
Lan Zhou, MD, PhD
MemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: lan.zhou@case.edu
Phone: 216.368.1671
My labs studies Notch signaling in stress hematopoiesis, hematopoietic stem cell niche, and leukemia microenvironment. Additional projects include pathogenesis of inflammation-associated colorectal cancer mouse models and targeting pancreatic cancer metabolic vulnerability and drug resistance.
Xiaofeng Zhu, PhD
ProfessorDepartment of Epidemiology and BiostatisticsSchool of MedicineFacultyCleveland Institute for Computational BiologyEmail: xxz10@case.edu
Phone: 216.368.0201
We are focused on developing statistical and deep learning methods, along with software and bioinformatic tools, for analyzing genetic and genomic data. Additionally, we aim to understand the biological mechanisms underlying various disease phenotypes, including cardiovascular disease, hypertension, obesity, sleep disorders, and Alzheimer's Disease.
Shiwei Zhu, PhD
Assistant ProfessorDepartment of Physiology and BiophysicsSchool of MedicineEmail: shiwei.zhu@case.edu
Phone: 216.368.3400
We are interested in utilizing an advancing imaging technique, cryo-electron tomography, to visualize antimicrobial protein complexes directly in their native cellular context. We also employ cryo-EM single particle analysis and other biophysical techniques to study the structure and mechanism of antimicrobial macromolecular complexes. We aim to provide essential structural information to help develop strategies to combat infectious diseases.
Xiongwei Zhu, PhD
ProfessorDepartment of PathologySchool of MedicineProfessorDepartment of NeurologySchool of MedicineCo-Director, Pathology Graduate ProgramDepartment of PathologySchool of MedicineDirector, Molecular and Cellular Basis for Disease Training ProgramDepartment of PathologySchool of MedicineEmail: xiongwei.zhu@case.edu
Phone: 216.368.5903
My lab studies pathogenic mechanisms underlying neurodegeneration in age-related neurodegenerative diseases including Alzheimer's disease and Parkinson disease with a focus on mitochondrial dysfunction and oxidative stress. A variety of experimental systems are used, including primary and transformed neuronal cells and multiple mouse models representing these disorders as well as brain tissues from human patients.
Richard Zigmond, PhD
ProfessorDepartment of NeurosciencesSchool of MedicineProfessorDepartment of Neurological SurgerySchool of MedicineProfessorDepartment of PathologySchool of MedicineEmail: rez@case.edu
Phone: 216.368.4614
I focus on changes in neuronal gene expression after injury and their relationship to nerve regeneration. I study the role of immune cells in nerve degeneration and regeneration, and compare nerve regeneration in different types of sensory neurons.
Peter A. Zimmerman, PhD
ProfessorDepartment of PathologySchool of MedicineProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineProfessorDepartment of Genetics and Genome SciencesMemberCenter for Global Health and DiseasesSchool of MedicineEmail: peter.zimmerman@case.edu
Phone: 216.368.0508
I interrogate molecular sequence polymorphism associated with susceptibility and resistance to infectious diseases.