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Kurt W. Runge, PhD
Associate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: rungek@ccf.org
Phone: 216.445.9771
My areas of investigation include regulation of the length of telomere repeats and their role in cell physiology, genetic pathways controlling gene silencing and cell aging, and the biology and biochemistry of vitamin K in mammals.
Jiri Safar, MD
ProfessorDepartment of PathologySchool of MedicineProfessorDepartment of NeurologySchool of MedicineMemberCleveland Center for Membrane & Structural BiologySchool of MedicineEmail: jiri.safar@case.edu
Phone: 216.368.4609
My areas of research include protein misfolding, structure-function correlations, amyloid immunochemistry, age-related neurodegeneration, transgenic mice therapeutics, translational medicine, prion diseases, and Alzheimer’s disease.
Helen Salz, PhD
ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: helen.salz@case.edu
Phone: 216.368.2879
Our lab studies germ cell development. We take advantage of the many genetic, molecular and cell biological tools available in Drosophila to define how sex is determined and maintained in female germ cells, and why errors in this process leads to infertility and germ cell tumors.
Ashleigh Schaffer, PhD
Vice Chair for EducationDepartment of Genetics and Genome SciencesSchool of MedicineAssociate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineAssociate ProfessorCenter for RNA Science and TherapeuticsSchool of MedicineEmail: ashleigh.schaffer@case.edu
Phone: 216.368.1892
I focus on the genetics of neurodevelopmental disorders and pediatric-onset neurodegeneration, including tissue-specific requirements of ubiquitously expressed proteins in development and disease.
Ashleigh Schaffer's Biography
Jeffrey Schelling, MD
ProfessorDepartment of Physiology and BiophysicsSchool of MedicineEmail: jeffrey.schelling@case.edu
Phone: 216.368.1100
We primarily utilize molecular and advanced imaging techniques in cells and mouse models to imterrogate pathophysiologic mechanisms of diabetes and diabetic kidney disease.
William P. Schiemann, PhD
Vice Dean for ResearchSchool of MedicineGoodman-Blum Professor in Cancer ResearchSchool of MedicineProfessorDepartment of BiochemistrySpecial Advisor to the DirectorCase Comprehensive Cancer CenterDirectorPilot Funding & Scientific InvestmentsCase Comprehensive Cancer CenterMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: William.Schiemann@case.edu
Phone: 216.368.5763
I focus on molecular mechanisms of breast cancer metastasis, metastatic dormancy, and metastastic relapse.
William P. Schilling, PhD
ProfessorDepartment of Physiology and BiophysicsSchool of MedicineVice ChairDepartment of Physiology and BiophysicsSchool of MedicinePhone: 216.778.8965
I research the molecular mechanisms of agonist-induced Ca2+ signaling in mammalian non-excitable cells: TRP family channels.
Alvin H. Schmaier, MD
ProfessorDepartment of MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: schmaier@case.edu
Phone: 216.368.1172
My primary research is in vascular biology of factor XII, kallikrein/kinin, renin-angiotensin, coagulation and complement systems, cancer and thrombosis, immunology of vascular thrombosis, tyrosine kinase inhibitors and vascular inflammation, ponatinib, malaria, COVID-19 pneumonia, and hereditary angioedema.
Fredrick R. Schumacher, PhD, MPH
Associate ProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineCo-LeaderPopulation and Cancer Prevention ProgramCase Comprehensive Cancer CenterFacultyCleveland Institute for Computational BiologyEmail: frs2@case.edu
Phone: 216.368.0351
My research interests as a genetic epidemiologist focuses on three major areas - deciphering the genomic architecture of complex traits, assessing the shared genomic etiology of complex phenotypes to elucidate the underlying biology, and ascertaining the clinical impact of genomics. My research primarily focuses on cancer by utilizing computational tools.
Jacob Scott (he/him), MD, DPhil
Associate ProfessorDepartment of Molecular MedicineSchool of MedicineAdjunct Associate ProfessorDepartment of PhysicsSchool of MedicineAssociate Director for Data SciencesCase Comprehensive Cancer CenterMemberDevelopmental Therapeutics ProgramCase Comprehensive Cancer CenterEmail: jgs25@case.edu
Our lab studies cancer and pathogen evolution using theoretical models (mathematical/computational), experimental evolution (in vitro) and data science methods (-omics and AI/ML).