Search results, if found, will automatically update as terms are selected. If no results are displayed, please revise your search terms.
Filter By:
Apollo Stacy, PhD
Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterMemberCenter for Microbiome and Human HealthLerner Research InstituteEmail: stacya2@ccf.org
We communicate with our resident microbiota through the language of metabolites. Host-derived metabolites shape the balance between commensals and pathogens, and in turn, microbiota-derived metabolites tune host immune responses. This dialogue ultimately determines our susceptibility to disease. We use bacterial genetics, genomics, animal models, and immune profiling to decipher microbiota-host metabolic communication in the oral cavity, site of one of the most prevalent inflammatory diseases worldwide (periodontitis).
Jonathan Stamler
PresidentHarrington Discovery InstituteDirectorInstitute for Transformative Molecular MedicineSchool of MedicineMy primary research is in redox-based cellular regulation and signal transduction, and in particular the role of protein S-nitrosylation.
Catherine M. Stein, PhD
ProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineEmail: catherine.stein@case.edu
Phone: 216.368.5631
Dr. Catherine M. Stein’s primary research focus is on genetic and environmental susceptibility to tuberculosis (TB), specifically the genomics of resistance and how genetic variation in both humans and the tuberculosis pathogen influence TB severity. Dr. Stein also works on speech-sound disorder, building upon more than two decades of Case Western Reserve University study.
Julian E. Stelzer, PhD
ProfessorDepartment of Physiology and BiophysicsSchool of MedicineEmail: julian.stelzer@case.edu
Phone: 216.368.8636
Our lab studies molecular and in vivo mechanisms of cardiac regulation. We focus on the role of contractile proteins in modulation of mechanical and hemodynamic function in genetic and aquired heart failure. We use biophysical techniques, in vivo cardiovascular phenotyping, and gene replacement approaches to develop novel therapies that improve contractile function in heart failure.
Ruben Stepanyan
Assistant ProfessorSchool of MedicineOur lab focuses on the physiology of mechanosensory cells of the inner ear; receptors for senses of hearing and balance; in mouse and zebrafish models; electrophysiology, optical and electron microscopy imaging.
Phoebe L. Stewart, PhD
ProfessorDepartment of PharmacologyCase Western Reserve UniversitySchool of MedicineMemberCleveland Center for Membrane and Structural BiologyMemberDevelopmental Therapeutics ProgramCase Comprehensive Cancer CenterEmail: pls47@case.edu
Phone: 216.368.4349
Our lab studies the structure of engineered adenovirus vectors and their complexes with immune molecules. More specifically we focus on understanding the molecular mechanisms underlying systemic inflammation and how targeted viral capsid mutations might alter host-pathogen interactions. We utilize cryo-electron microscopy (cryo-EM) single particle reconstruction and tomography, molecular dynamics and molecular modeling.
J. Michael Stolley, PhD
Assistant StaffCleveland ClinicEmail: stollej5@ccf.org
We are interested in understanding the functional implications of oral resident memory T cells on various aspects of oral physiology and disease. To address these questions, we utilize mouse models of oral viral infections and oral inflammatory diseases including periodontitis. We are also interested in understanding whether local T-cell driven inflammatory responses in the oral mucosa impact chemosensory biology (e.g., taste and smell).
Ben W. Strowbridge, PhD
ProfessorDepartment of NeurosciencesSchool of MedicineProfessorDepartment of Physiology and BiophysicsSchool of MedicineEmail: bens@case.edu
Phone: 216.368.6974
My research includes synaptic physiology, hippocampus, olfactory bulb and computational neuroscience.
Carlos Subauste , MD
ProfessorMedicine and PathologySchool of MedicineEmail: carlos.subauste@case.edu
Phone: 216.368.2785
My Laboratory is dedicated to the study of cell signaling to develop novel therapies against infectious and inflammatory diseases. This work includes translational studies in animal models of these diseases.
Carlos Subauste's BiographyQian Sun, PhD
Assistant ProfessorDepartment of NeurosciencesSchool of MedicineEmail: qxs111@case.edu
Phone: 216.368.4169
Our lab studies the function of the hippocampal circuit, a brain area that is vital for memory formation and is linked to many neuropsychiatric disorders, such as PTSD, schizophrenia, and Alzheimer's disease. We use a variety of in vitro and in vivo techniques – including electrophysiology, neuronal tracing, optogenetics and chemogenetics, immunohistochemistry, and mouse behavior – to address the cellular and circuit mechanisms underlying hippocampal information processing and its relevance to behaviors.