For more information, contact Susan Griffith, 216-368-1004 or sbg4@po.cwru.edu.

HEALING WITH LIGHT (running time = 1:44)

View a QuickTime version of this video online. (Download QuickTime.)

SUGGESTED INTRO: ADVANCES IN PHOTO-BLEACH LAUNDRY PRODUCTS ARE HELPING RESEARCHERS DEVELOP WEAPONS AGAINST CANCER. THE COMBINED TECHNOLOGY WILL LET DOCTORS SPARE OTHERWISE HEALTHY TISSUE WHEN DESTROYING TUMORS. MORE IN THIS REPORT:

VIDEO: Open with shot of lab worker in cancer laboratory. Cut to CU of photo-sensitive chemical in breaker. Cut to woman walking in front of Agnar Pytte Research Bldg. at CWRU. Cut to CU of bottle of P-C-4 photo-chemical held by researcher. Cut to P-C-4 in front of red light projector. Cut to CU of red lights. Cut to CU of lab worker's hands with test vials.

VOICEOVER: THE CHALLENGE OF TREATING CANCER HAS TAKEN A NEW TURN WITH THE APPLICATION OF LIGHT-ACTIVATED DRUGS. AT CASE WESTERN RESERVE UNIVERSITY, RESEARCHERS ARE TARGETING TUMORS WITH A DRUG CALLED P-C-4. LONGER WAVELENGTH RED LIGHT ACTIVATES P-C-4 WHICH SELECTIVELY KILLS CANCER CELLS, BUT SPARES SURROUNDING HEALTHY TISSUE. PROFESSOR MALCOLM KENNEY IS WORKING TO IMPROVE P-C-4.

SOT & SUGGESTED SUPER: Malcolm Kenney, CWRU professor of chemistry

INTERVIEW: "This kind of therapy depends very much on the dye that's used and the dye that is approved now has some problems with it and so we've been trying to develop what are called 2nd generation kind of dyes." (TRT :14)

VIDEO: Procter & Gamble lab worker writes in journal. Cut to P&G signage at headquarters.

Cut to lab worker viewing chemicals under microscope.

Cut to shot of the sun (sunburst).

Cut to P&G Tide assembly line.

VOICEOVER: EVEN BETTER PHOTO-SENSITIVE DRUGS MAY BE ON THE WAY THANKS TO A PATENT GIFT FROM PROCTER AND GAMBLE. THEY'VE GIVEN CASE WESTERN RESERVE THE RIGHTS TO THEIR APOLLO PHOTO-CHEMICAL TECHNOLOGIES WHICH INCLUDE LIGHT-SENSITIVE BLEACHES THAT REMOVE STAINS FROM CLOTHING WHEN EXPOSED TO SUNLIGHT. THE PRODUCTS SELL MOSTLY IN COUNTRIES WHERE LINE-DRYING IS POPULAR.

ON-CAMERA INTERVIEW: Malcolm Kenney, CWRU professor of chemistry

VIDEO: Cut to shot of beakers in Malcolm Kenney's lab at CWRU. Cut to Kenney and another researcher viewing computer model of photo-chemical. Cut to 3D computer model on-screen. Cut back to Kenney on-camera.

INTERVIEW: Since the chemistry of these photo-bleaches is similar to the chemistry that is used in photo-dynamic therapy, they thought we might be able to collaborate together and develop a new set of dyes that would be particularly efficient as photo-bleaches. It's the idea of using the information that comes out of one area of research for the other area of research. There is a great deal of cross-fertilization here. (TRT :29)

VIDEO: Cut to shot of photo-chemical being mixed in beaker. Cut to wide 2-shot of Kenney and another researcher in lab at CWRU.

Cut to black.

VOICEOVER: CASE WESTERN RESERVE PLANS TO MARKET PHOTO-SENSITIVE CANCER DRUGS AND SUN-BLEACHING LAUNDRY PRODUCTS TO A WORLDWIDE MARKET.

THIS IS DAVE NAROSNY REPORTING FROM CASE WESTERN RESERVE UNIVERSITY, CLEVELAND.


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