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Cut to CU of centrifuge. |
VOICEOVER: IT MIGHT BE ON A MISSION TO MARS OR ORBITING THE EARTH, BUT EVENTUALLY HUMANS WILL BE BORN IN SPACE. NASA WANTS TO KNOW IF ALTERED GRAVITY MIGHT POSE A RISK TO DEVELOPING EMBRYOS AND FUTURE SPACE MOMS TOO. ENTER THE ZEBRAFISH. THESE TINY SWIMMERS ARE A GOOD MODEL FOR THE HUMAN VESTIBULAR SYSTEM, WHICH CONTROLS BALANCE AND AGILITY. AT CASE WESTERN RESERVE UNIVERSITY, STEPHEN MOORMAN IS SIMULATING THE WEIGHTLESSNESS OF SPACE AS EGGS BECOME FISH. THE CHANGES HE'S FOUND FROM NORMAL ZEBRAFISH ARE -- LARGE SCALE. |
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SOT & SUGGESTED SUPER: Stephen Moorman, CWRU assistant professor of anatomy VIDEO:Cut-away to zebrafish swimming. Cut to time-lapse of zebrafish embryo developing. |
INTERVIEW: And since the light was above these baby fish, they were using that to orient themselves. When we put the light underneath them they swam upside down and so they obviously couldn't tell which way is down based on which way gravity was pulling and so that was our first indication that their vestibular system didn't work. The vestibular system in the zebrafish is almost identical to the vestibular system in humans. The suggestion there is that the genes that control its development are probably very similar also. (TRT :28) |
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VOICEOVER: MOORMAN HOPES TO DETERMINE IF THERE IS A KEY TIME DURING PREGNANCY WHEN A WOMAN SHOULD SEEK EARTH-LIKE GRAVITY CONDITIONS. |
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VIDEO: ON-CAMERA INTERVIEW: Stephen Moorman |
INTERVIEW: If a baby is conceived in space and born in space, if you want that child to be able to come back to Earth and be able to maintain balance while they're walking, then you're probably going to have to expose that child sometime during its development to normal gravity. (TRT :16) |
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Cut to CU of Stephen Moorman looking into microscope. Cut to overhead shot of space station. Cut to black. |
ZEBRAFISH WILL BE SWIMMING ON FUTURE SPACE STATION AND SHUTTLE MISSIONS TO GET BETTER ANSWERS FOR FUTURE GENERATIONS LIVING FAR FROM EARTH. THIS IS DAVE NAROSNY REPORTING FROM CASE WESTERN RESERVE UNIVERSITY, CLEVELAND. |