Artificial human chromosomes script

For more information regarding this feature, contact George Stamatis by sending e-mail to gxs18@po.cwru.edu or by calling 1-800-368-CWRU.

ARTIFICIAL HUMAN CHROMOSOMES (running time = 1:45)

SUGGESTED INTRO: FOR THE FIRST TIME, RESEARCHERS HAVE CREATED ARTIFICIAL HUMAN CHROMOSOMES, A MAJOR STEP IN THE EFFORT TO TREAT DISEASE BY GENE THERAPY. MORE IN THIS REPORT:

[VIDEO] CWRU signage. Tracking shot of lab research assistant. Close-up of chromosomal sample vials.

[SCRIPT] RESEARCHERS AT CASE WESTERN RESERVE UNIVERSITY HAVE CREATED ARTIFICIAL HUMAN CHROMOSOMES. DEVELOPERS SEE THEM AS A KEY TOOL OF GENE THERAPY. DOCTOR JOHN HARRINGTON EXPLAINS.

[VIDEO] On-camera interview sound bite.

[SOT & SUGGESTED SUPER] DR. JOHN HARRINGTON, CWRU GENETICIST

(OUTCUE: "...of normal human chromosomes.") ( :15)

[VIDEO] Close-up of chromosomal sample vials. Cut to wide shot of lab worker. Cut to 2-shot of J. Harrington and H. Willard in lab. Cut to microscopic photo of artificial chromosome (stained) among natural chromosomes (blue). On-camera interview sound bite.

[SCRIPT] GENE THERAPY COULD PREVENT OR CURE DISEASE BY CHANGING A CELL'S GENETIC STRUCTURE, BUT GENES MUST ENTER A CELL AND REMAIN STABLE THROUGH CELL DIVISION TO BE EFFECTIVE. HUNTINGTON WILLARD, SENIOR STUDY AUTHOR, SAYS THEY'VE PASSED THAT HURDLE.

[SOT & SUGGESTED SUPER] DR. HUNTINGTON F. WILLARD, CWRU GENETICIST

(OUTCUE: "...for that function, until this study.") ( :49)

[VIDEO] 2 graphics of artificial human chromosomes. Cut to microscopic photo of artificial chromosome (stained) among natural chromosomes (blue). Cut to lab shot of Harrington and Willard.

[SCRIPT] RESEARCHERS BELIEVE ARTIFICIAL CHROMOSOMES WILL EVENTIALLY TREAT IMMUNE SYSTEM DISORDERS, BLOOD DISORDERS LIKE SICKLE CELL ANEMIA, AND MANY OTHERS. THIS IS DAVE NAROSNY REPORTING FROM CASE WESTERN RESERVE UNIVERSITY, CLEVELAND.

-CWRU-