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Lactamase Group

 
 

Cleveland's

joint VA/Case/CSU

ß-lactamase group

 

Research Mission


 

Our goal is to study the major human threat of antibiotic resistance using an inter-disciplinary collaborative approach involving molecular, microbiological, biochemical, and biophysical techniques. Our inter-institutional team is ranging from basic science researchers to clinical researchers with a strong focus in investigating current antibiotics and ß-lactamase inhibitors, their efficacy against inhibitor resistant and extended-spectrum ß-lactamases, and development of novel therapeutic strategies.

Participating Cleveland institutions:

Louis Stokes Cleveland Department of Veterans Affairs Medical Center (VA)

- Center for Antimicrobial Resistance and Epidemiology

Case Western Reserve University (Case)

- Division of Infectious Diseases

- Department of Biochemistry

- Department of Pharmacology

Cleveland State University (CSU)

- Department of Chemistry

Participating non-Cleveland institution:
Southern Methodist University (SMU)