case western reserve university





Musa A. Haxhiu, M.D., Ph.D.

Ventral Medullary Network & Cardiorespiratory Regulation

Central autonomic control of respiration and cardiovascular systems. Neuronal networks involved in coordination of respiratory activity and cholinergic outflow to the airways. Excitatory amino acids and excitatory amino acid receptors in airway reflex responses. Interaction between excitatory amino acids and tachykinin peptides in processing afferent inputs to brainstem network. Adrenergic, cholinergic, peptidergic and nitric oxide related pathways and their role in the control of airway vasculature. Signal transduction pathways involved in neurogenic inflammation. Central chemosensory systems: structure-function relationship.

Selected References:

Haxhiu, M.A., A.S.P. Jansen, N.S. Cherniack, and A.D. Loewy. CNS innervation of airway-related parasympathetic preganglionic neurons: a transneuronal labeling study using pseudorabies virus. Brain Res. 618:115-138, 1993.

Loewy, A.D., Franklin, M.F., Haxhiu, M.A. CNS monamine cell groups projecting to pancreatic vagalmotor neurons: a transneuronal labeling study using pseudorabies virus. Brain Res. 1994; 638:284-260.

Haxhiu, M.A., Erokwu, B.O., Cherniack, N.S. The brainstem network involved in coordination of inspiratory activity and cholinergic outflow to the airways. J. Autonomic Nerv. System. 61(2): 155-161, 1996.

Haxhiu, M.A., and A.D. Loewy. Central connections of the motor and sensory vagal systems innervating the trachea. J. Autonomic Nerv. System 57:49-56, 1996.

Haxhiu, M.A., K. Yung, B. Erokwu, and N.S. Cherniack. CO2-induced c-fos expression in the CNS catecholamingeric neurons. Respir. Physiol., 105(1-2): 35-45, 1996.

Haxhiu, M.A., Erokwu, B., and Dreshaj, I.A. The role of excitatory amino acids in airway reflex responses in anesthetized dogs. J. Auton. Nerv. System, 67: 192-199, 1997.

Dept. of Anatomy | 10900 Euclid Ave. | Cleveland, Ohio 44106-4930 | Phone:216.368.2433|
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