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Musa A. Haxhiu, M.D., Ph.D.
Ventral Medullary
Network & Cardiorespiratory Regulation
Central autonomic control
of respiration and cardiovascular systems.
Neuronal networks involved in coordination of
respiratory activity and cholinergic outflow to
the airways. Excitatory amino acids and
excitatory amino acid receptors in airway reflex
responses. Interaction between excitatory amino
acids and tachykinin peptides in processing
afferent inputs to brainstem network.
Adrenergic, cholinergic, peptidergic and nitric
oxide related pathways and their role in the
control of airway vasculature. Signal
transduction pathways involved in neurogenic
inflammation. Central chemosensory systems:
structure-function relationship.
Selected References:
Haxhiu, M.A., A.S.P.
Jansen, N.S. Cherniack, and A.D. Loewy. CNS
innervation of airway-related parasympathetic
preganglionic neurons: a transneuronal labeling
study using pseudorabies virus. Brain Res.
618:115-138, 1993.
Loewy, A.D., Franklin, M.F.,
Haxhiu, M.A. CNS monamine cell groups projecting
to pancreatic vagalmotor neurons: a
transneuronal labeling study using pseudorabies
virus. Brain Res. 1994; 638:284-260.
Haxhiu, M.A., Erokwu, B.O.,
Cherniack, N.S. The brainstem network involved
in coordination of inspiratory activity and
cholinergic outflow to the airways. J.
Autonomic Nerv. System. 61(2): 155-161,
1996.
Haxhiu, M.A., and A.D.
Loewy. Central connections of the motor and
sensory vagal systems innervating the trachea.
J. Autonomic Nerv. System 57:49-56, 1996.
Haxhiu, M.A., K. Yung, B.
Erokwu, and N.S. Cherniack. CO2-induced
c-fos expression in the CNS catecholamingeric
neurons. Respir. Physiol., 105(1-2):
35-45, 1996.
Haxhiu, M.A., Erokwu, B.,
and Dreshaj, I.A. The role of excitatory amino
acids in airway reflex responses in anesthetized
dogs. J. Auton. Nerv. System, 67:
192-199, 1997. |
