Mt Sinai Auxiliary Professor and Chair Department of Nutrition | CASE School of Medicine
Director | CASE Mouse Metabolic Phenotyping Center
RESEARCH Regulations of the pathways of intermediary metabolism investigated by metabolomics coupled with stable isotope technologies.
Leonard and Jean Skeggs Professor Department of Biochemistry | CASE School of Medicine
RESEARCH Control of gluconeogenesis and regulation of the turnover of triglyceride in mammals.
Professor Department of Pharmacology | CASE School of Medicine
RESEARCH Regulation of gene expression by nuclear hormone receptors and their ligands. Special focus on the roles of retinoid receptors in cancer and diabetes.
Mary Blossom Lee Chair in Pediatric Diabetes Pediatric Endocrinology | UH Case Medical Center
Assistant Professor Pediatric Endocrinology | UH Case Medical Center
PI EDIC Clinical Coordinating CenterRESEARCH Pediatric Endocrinology - Diabetes - Metabolism.
Jules and Doris Stein Professor Departments of Ophthalmology (primary) and Pharmacology (secondary) CASE School of Medicine
RESEARCH Pharmacologic stimulation of cholesterol turnover in the brain and the link between cholesterol and diseases of the retina.
David N. and Inez Myers/Antonio Scarpa Professor Department of Physiology & Biophysics CASE - School of Medicine
RESEARCH Mechanism of ion and molecules transfer across various sections of the mammalian nephron, using molecular biology and cell biology techniques. Emphasis is on the bicarbonate transporter and its regulation.
Professor Department of Physiology & Biophysics | CASE School of Medicine
RESEARCH Fundamental aspects of nucleotide-based signal transduction: (i) the physiological and pathological roles of extracellular ATP in various pro-inflammatory cascades, and (ii) the mechanisms by which ATP and other nucleotides are released into, and metabolized within extracellular compartments.
Chair Department of Pathobiology Cleveland Clinic | Lerner Research Institute
Joint Staff The Respiratory Institute
RESEARCH Asthma, Exhaled markers in lung disease, lung biology and physiology, pulmonary hypertension, Nitric oxide (NO) in lung physiology and disease.
Robert Canova Professor Department of Cellular & Molecular Medicine
Cleveland Clinic Lerner Research Institute
RESEARCH Metabolic pharmacology defined as the study of the mechanisms of action of therapeutic agents with potential in metabolic diseases such as insulin resistance syndrome.
Carter Kissell Associate Professor and Research Director
Department of Urology | CASE School of Medicine
RESEARCH Metabolism of prostate cancer.
Professor Department of Nutrition | CASE School of Medicine
RESEARCH Nutrient control of gene expression and the characterization of adaptive responses of cells to limited supply of nutrients.
The Jan Bleeksma Chair Vascular Cell Biology and Atherosclerosis
The Leonard Krieger Chair Preventive Cardiology
Chair Department of Cellular & Molecular Medicine | Cleveland Clinic Lerner Research Institute
Director Center for Cardiovascular Diagnostics & Prevention Section Head, Preventive Cardiology & Rehabilitation
RESEARCH Inflammation; Atherosclerosis; Asthma; Metabolomics; Myeloperoxidase; Cardiovascular diseases; HDL; Peroxidases; Airway remodeling; Intestinal microbiota; Gut flora; Cardiometabolic diseases.
Professor of Medicine Clinical and Molecular Endocrinology | CASE School of Medicine
RESEARCH Bioenergetics and the control of ATP production and utilization; Diabetes; Thyroid Disease.
Ellery Sedgwick Jr. Chair and Distinguished Scientist UH Case Medical Center
Professor and Director Cardiovascular Research Institute | UH Case Medical Center
RESEARCH Transcriptional mechanisms governing cellular differentiation and function, highlighting the importance of a family of factors termed Kruppel-like factors that regulate critical aspects of heart, blood vessel, and immune cell biology.
Professor Department of Pathobiology - Cleveland Clinic | Lerner Research Institute
RESEARCH Metabolic adaptive responses of the mother during normal pregnancy and the role of maternal insulin resistance on maternal protein metabolism and fetal growth, the significance and mechanism of insulin resistance in puberty, and the consequence of insulin resistance on muscle protein metabolism in liver disease.
Professor Departments of Medicine (Clinical and Molecular Endocrinology) and Pharmacology
CASE School of Medicine
RESEARCH Causes and mechanisms of diabetic retinopathy (a leading cause of acquired blindness among young adults in the US) and how it can be prevented.
Associate Professor Department of Gastroenterology & Hepatology | Cleveland Clinic Lerner Research Institute
Secondary Appointment Department of Pharmacology | CASE School of Medicine
RESEARCH (1) How exercise and diet alter the disease risks associated with insulin resistance, obesity, type 2 Diabetes and cardiovascular disease in the elderly; (2) How aerobic exercise training and dietary restriction interventions improve cardio-respiratory function and reverse insulin resistance in the elderly.
Professor Departments of Pharmacology and Molecular Biology and Microbiology
CASE School of Medicine
RESEARCH The multiple roles of Mg2+ Transport and Mn2+ in bacterial metabolism and pathogenesis using primarily Salmonella Typhimurium as a model system.
Associate Professor Department of Nutrition | CASE School of Medicine
RESEARCH Molecular-level treatment and prevention of cancer.
Assistant Professor (Molecular Medicine) Department of Pathobiology | Cleveland Clinic Lerner Research Institute
RESEARCH Molecular mechanisms involved in inflammatory bowel disease pathogenesis with a particular focus on anti-microbial responses mediated by the bacterial sensor NOD2.
Professor Department of Pharmacology | CASE School of Medicine
RESEARCH Enzymatic reaction mechanisms involved in intracellular sulfhydryl homeostasis and redox signal transduction in health and diseases, including cancer, cardiovascular and neurological disorders, and diabetes.
Professor Department of Pathology | CASE School of Medicine
RESEARCH Molecular mechanisms of protein aging, oxidative stress, complications of diabetes and aging, cataractogenesis, microbial enzyme technology: the chemistry and biology of amino-carbonyl reactions in the aging human lens. The Maillard reaction is initiated by the nonenzymatic condensation of highly reactive carbonyl compounds derived from reducing sugars, such as glucose, ascorbic acid, or the oxoaldehydes glyoxal and methylglyoxal.
Professor Department of Pathobiology | Cleveland Clinic Lerner Research Center
Secondary Appointment Department of Nutrition | CASE School of Medicine
RESEARCH The molecular mechanisms of alcoholic liver disease, focusing particularly on the effects of ethanol on receptor-dependent signal transduction.
Staff Scientist Center for Reproductive Health R358 - Department of OB/GYN, MetroHealth Medical Center | Cleveland, OH
RESEARCH Metabolism of fatty acids in the placenta.
John H. Hord Professor and Chair Department of Pharmacology
CASE School of Medicine
RESEARCH To understand the retinoid metabolism. Specifically, our focus is on (1) the retention of retinoids and (2) isomerization of all-trans-retinyl esters to 11-cis-retinol, a fundamental process of the chromophore formation essential for our vision around.
Charles Fredrick Mabery Professor of Research in Chemistry Department of Chemistry
CASE College of Arts and Sciences
RESEARCH Biochemistry, Chemical Biology, Medicinal Chemistry, Organic Chemistry, Bio-Organic Chemistry, Cellular Biology, Molecular Biology, Natural Products, Pharmacology, Synthesis.
Associate Professor Department of Chemistry | CASE College of Arts and Sciences
RESEARCH Chemical Biology; Metabolomics coupled with stable isotope technology; Medicinal Chemistry; Bioorganic Chemistry.
Associate Professor Department of Pharmacology | CASE School of Medicine
RESEARCH Metabolism of retinoids in relation to metabolic control, cell proliferation and, vision.
Chair Department of Biochemistry | CASE School of Medicine
Cowan-Blum Professor of Cancer Research
Professor of Biochemistry and Medicine Division of Endocrinology | CASE School of Medicine
RESEARCH Control of gene expression and protein folding and misfolding. Links are made to clinical phenotypes or disease mechanisms. Studies of gene expression include analysis of mammalian and viral transcription factors.
Charles J. Epstein Professor of Human Genetics and Pediatrics
Chief, Division of Medical Genetics
Department of Pediatrics and Institute of Human Genetics | UCSF School of Medicine
RESEARCH Metabolic effects of inborn disorders of metabolism
Associate Professor Department of Biomedical Engineering | CASE School of Medicine
RESEARCH Cardiovascular physiology; magnetic resonance imaging and spectroscopy; characterization of the structure-function and energy–function relationships in normal and diseased hearts; small animal imaging and spectroscopy.
Case School of Medicine is home to close to 30 Centers and Institutes. As a result, medical students are able to pursue areas of interest in great depth. Read more...
Have a question? From deadlines to requirements, please email Dr. Henri Brunengraber (Program Director) at: hxb8@case.edu
