319 Wickenden Building (7207)
Phone 216-368-4063; Fax 216-368-4969
Patrick E. Crago, Chair
e-mail xx220@po.cwru.edu
http://bme.cwru.edu

Biomedical engineering (BME) uniquely advances human health and the biological sciences by creating and applying technology based on phenomena described by the biological and physical sciences. Graduates in biomedical engineering are employed in industry, hospitals, research centers, government, and universities. Biomedical engineers also use their undergraduate training as a basis for careers in business, medicine, law, and other professions.

Biomedical engineering was established in 1968 at Case Western Reserve University. As one of the pioneer programs in the world, we now have a strong and well-established program in research and education with many unique features. It was founded on the premise that engineering principles provide an important basis for innovative and unique solutions to biomedical problems. This philosophy has been the guide for the successful development of our program, which has been emulated by many other institutions. Quantitative engineering for biomedical applications remains the cornerstone of our program and distinguishes it from biomedical science programs. In addition to dealing with biomedical problems at the tissue and organ-system level, our educational programs have a growing emphasis on cellular and subcellular mechanisms for understanding of fundamental processes as well as for systems approaches to solving clinical problems. Current programs lead to the B.S., M.S., combined B.S./M.S., Ph.D., and MD/Ph.D. in biomedical engineering. In all of the BME programs at Case Western Reserve, the goal is to educate engineers who can apply engineering methods to problems involving living systems. The Case School of Engineering and the School of Medicine are located in close proximity on the same campus. The Biomedical Engineering faculty carry joint appointments in the two schools and participate fully in the teaching, research, and decision-making committees of both schools. The department is in close proximity to several major medical centers (University Hospitals, Cleveland Clinic Foundation, The VA Medical Center, and MetroHealth Medical Center). As a result, we have an unusually free flow of academic exchange and collaboration in research and education among the Schools and Institutions. Our BME programs take full advantage of faculty cooperation among University departments, which adds significant strength to our programs.

The educational philosophy is to develop in students

Patrick E. Crago, Ph.D. (Case Western Reserve University)
Professor and Chairperson; Allen H. and Constance T. Ford Professor
Control of neuroprotheses for motor function; neuromuscular control systems

Ravi V. Bellamkonda (Brown University)
Associate Professor
Biomaterials; neural tissue engineering; 3D hydrogel based scaffolds; gene and protein delivery vehicles; vascular grafts and nerve regeneration

Jianmim Cui, Ph.D. (State University of New York - Stony Brook)
Assistant Professor
Molecular and biophysical mechanisms of ion channel function and modulation; the role of ion channels in cardiac excitation and arrhythmias

Cheri Deng, Ph.D. (Yale University)
Elmer W. Lindseth Assistant Professor, Biomedical Engineering
Research in ultrasound, contrast agents and angiogenesis

Dominique Durand, Ph.D. (University of Toronto, Canada)
Professor
Director, Neural Engineering Center
Neural engineering; neuroprostheses; neural dynamics; electric and magnetic stimulation of the nervous system; neural interfaces with electronic devices; analysis and control of epilepsy

Steven J. Eppell, Ph.D. (Case Western Reserve University)
Assistant Professor
Nanoscale instrumentation for biomaterials; bone and cartilage

Igor Efimov, Ph.D. (Moscow Institute of Physics & Technology)
Elmer W. Lindseth Associate Professor of Biomedical Engineering
Fast fluorescent imaging of the heart. Mechanisms of arrhythmogenesis and antiarrhythmic therapies. Mechanisms of stimulation and defibrillation of the heart

Jinming Gao, Ph.D. (Harvard University)
Assistant Professor
Biomolecular engineering; imaging-guided drug delivery; controlled-release drug delivery; elastic biomaterials

Miklos Gratzl, Ph.D. (Technical University of Budapest, Hungary)
Associate Professor
Biochemical sensors; fine chemical manipulation of microdroplets and single cells; cancer research and neurochemistry at the single cell level; cost-effective biochemical diagnostics in microliter body fluids

Warren M. Grill, Ph.D. (Case Western Reserve University)
Assistant Professor of Biomedical Engineering
Neural engineering and neural prostheses; modeling and simulation of stimulation and electrodes; neural control of genitourinary and motor function; anatomy and neurochemistry of neural circuits

Robert F. Kirsch, Ph.D. (Northwestern University)
Associate Professor
Functional neuromuscular stimulation; biomechanics and neural control of human movement; modeling and simulation of musculoskeletal systems; identification of physiological systems

Dmitri E. Kourennyi, Ph.D. (Moscow Institute of Physics & Technology)
Assistant Professor
Synaptic transmission and networking in the retina; ion channels; biophysics, pharmacology, modulation; second messengers in neurons; nitric oxide functional and pathological roles; signal processing in the retina

Roger Marchant, Ph.D. (Case Western Reserve University)
Professor
Director, Center for Cardiovascular Biomaterials
Surface modification of cardiovascular devices; molecular level structure and function of plasma proteins; liposome drug delivery systems; mechanisms of bacterial adhesion to biomaterials

J. Thomas Mortimer, Ph.D. (Case Western Reserve University)
Professor Emeritus
Director, Applied Neural Control Laboratory
Neural prostheses; electrical activation of the nervous system; bowel and bladder assist device; respiratory assist device; selective stimulation and electrode development; electochemical aspects of electrical stimulation

Niels F. Otani, Ph.D. (University of California, Berkeley)
Associate Professor
Cardiac bioelectricity and excitable tissues; simulation of cardiac action potential propagation; nonlinear dynamics applied to excitable tissues; improved drug therapies and electrical intervention strategies for arrhythmias

P. Hunter Peckham, Ph.D. (Case Western Reserve University)
Professor
Director, Functional Electrical Stimulation Center
Neural prostheses, implantable stimulation and control; control of movement; rehabilitation engineering

Andrew M. Rollins, Ph.D. (Case Western Reserve University)
Assistant Professor, Biomedical Engineering
Biomedical diagnosis, novel optical methods for high-resolution, minimally invasive imaging, tissue characterization and analyte sensing, real-time microstructural and functional imaging using coherence tomography

Yoram Rudy, Ph.D. (Case Western Reserve University)
M. Frank & Margaret C. Rudy Professor of Cardiac Bioelectricity
Director, Cardiac Bioelectricity Research & Training Center (CBRTC)
Cardiac bioelectricity and electrophysiology of the heart; modeling cardiac excitation and arrhythmias at the cellular, tissue, and whole heart levels; cardiac mapping; noninvasive imaging of cardiac electrical function and arrhythmias

Gerald M. Saidel, Ph.D. (The Johns Hopkins University)
Professor
Mass & heat transport and metabolic analysis in cells, tissues, & organs; mathematical modeling, simulation, parameter estimation; optimal experimental design; metabolic dynamics; minimally invasive thermal tumor ablation; slow release drug delivery

David L. Wilson, Ph.D. (Rice University)
Professor
Medical image processing; image segmentation, registration, and analysis; quantitative image quality of X-ray fluoroscopy and fast MRI; interventional MRI treatment of cancer

James M. Anderson, Ph.D. (Oregon State University), M.D. (Case Western Reserve University)
Professor, Pathology, University Hospitals
Biocompatibility of implants

Harihara Baskaran, Ph.D. (Pennsylvania State University)
Assistant Professor, Chemical Engineering, Case Western Reserve University

Marco Cabrera, Ph.D. (Case Western Reserve University)
Assistant Professor, Pediatric Cardiology
Modeling and control of metabolic processes; metabolic regulation in hypoxia, ischaemia and exercise

Ronald L. Cechner, Ph.D. (Case Western Reserve University)
Associate Professor, Anesthesiology, University Hospitals
Microscopic 3-D imaging of tissue

John Chae, M.D. (New Jersey Medical School)
Assistant Professor, Physical Medicine and Rehabilitation
Application of neuroprotheses in hemiplegia

Hillel J. Chiel, Ph.D. (Massachusetts Institute of Technology)
Professor, Biology
Biomechanical and neural basis of feeding behavior in the marine mollusk Aplysia californica; neuromechanical system modeling; analysis of neural network dynamics

David Dean, Ph.D. (City University of New York)
Assistant Professor, Neurosurgery and Anatomy, University Hospitals
Morphometrics; craniofacial imaging

Louis F. Dell’Osso, Ph.D. (University of Wyoming)
Professor, Neurology, VA Medical Center
Neurophysiological and ocular motor control systems

Pedro J. Diaz, Ph.D. (Case Western Reserve University)
Assistant Professor, Radiology, MetroHealth Medical Center
Magnetic resonance imaging; image processing

Jeffrey L. Duerk, Ph.D. (Case Western Reserve University)
Professor, Radiology, University Hospitals
Magnetic resonance imaging; flow visualization

Brian Johnstone, Ph.D. (University College, University of London)
Assistant Professor, Orthopaedics, Case Western Reserve University

Michael W. Keith, M.D. (Ohio State University)
Professor, Orthopaedic Surgery, MetroHealth Medical Center
Restoration of motor function in hands

Kenneth R. Laurita, Ph.D. (Case Western Reserve University)
Assistant Professor, Cardiology, MetroHealth Medical Center
Optical imaging in cardiac electrophysiology

Zhenghong Lee, Ph.D. (Case Western Reserve University)
Assistant Professor, Radiology, Nuclear Medicine, University Hospitals

R. John Leigh, M.D. (University of Newcastle-Upon-Tyne, U.K.)
Professor, Neurology, VA Medical Center
Normal and abnormal motor control of the eye

Jonathan Lewin, M.D., Ph.D., (Yale University)
Professor, Radiology, University Hospitals

Raymond F. Muzic, Jr., Ph.D. (Case Western Reserve University)
Associate Professor, Radiology, University Hospitals
Experiment design and analysis for positron emission tomography

David S. Rosenbaum, M.D. (University of Illinois, Chicago)
Associate Professor, Medicine, MetroHealth Medical Center
Optical imaging in cardiac electrophysiology

Mark S. Rzeszotarski, Ph.D. (Case Western Reserve University)
Assistant Professor, Radiology, MetroHealth Medical Center
Radiological imaging; magnetic resonance imaging, ultrasound

Ronald J. Triolo, Ph.D. (Drexel University)
Associate Professor, Orthopaedics, VA Medical Center
Restoration of lower extremity function

Albert L. Waldo, M.D. (State University of New York)
Professor, Cardiology, University Hospitals
Cardiac electrophysiology and cardiac excitation mapping

Nicholas P. Ziats, Ph.D. (Case Western Reserve University)
Assistant Professor, Pathology, University Hospitals
Vascular grafts; vascular cells; blood vessels

Richard C. Burgess, M.D., Ph.D. (Case Western Reserve University)
Adjunct Professor of Biomedical Engineering (Neurological Computing, Cleveland Clinic Foundation)

Brian Davis, Ph.D. (Pennsylvania State University)
Adjunct Assistant Professor of Biomedical Engineering (Biomedical Engineering, Cleveland Clinic Foundation)
Human locomotion and biomechanics

Linda M. Graham, M.D. (University of Michigan)
Adjunct Professor of Biomedical Engineering (Vascular Surgery and Biomedical Engineering, Cleveland Clinic Foundation)

Hiroaki Harasaki, Ph.D., M.D. (Kyushu University, Japan)
Adjunct Associate Professor of Biomedical Engineering (Biomedical Engineering, Cleveland Clinic Foundation)
Artificial heart; blood-surface interactions

Vincent J. Hetherington, D.P.M. (Pennsylvania College of Podiatric Medicine)
Adjunct Assistant Professor of Biomedical Engineering (Surgery, Ohio College of Podiatric Medicine)
Biomaterials and biomechanics of foot prostheses

David Huang, Ph.D. (Massachusetts Institute of Technology), M.D. (Harvard University)
Adjunct Assistant Professor of Biomedical Engineering (Opthalmology, Cleveland Clinic Foundation)
Optical coherence tomography of the eye, laser vision correction, corneal wound healing, corneal topography

Joseph Izatt (Massaschusetts Institute of Technology)
Adjunct Associate Professor (Biomedical Engineering, Duke University)

J. Lawrence Katz, Ph.D. (Polytechnic Institute of Brooklyn)
Adjunct Professor (University of Missouri, Kansas City)
Bone biomechanics and biomaterials; bone mineral crystallography; ultrasonic wave propagation; scanning acoustic microscopy; dental and orthopaedic implants

Jill W. Kawalec, Ph.D. (Case Western Reserve University)
Adjunct Assistant Professor of Biomedical Engineering (Research Director, Ohio College of Podiatric Medicine)
Biomaterials and biomechanics of foot prostheses

Kevin L. Kilgore, Ph.D. (Case Western Reserve University)
Adjunct Assistant Professor of Biomedical Engineering (Orthopaedics, MetroHealth Medical Center)
Functional electrical stimulation; hand protheses

Melissa Knothe-Tate, Ph.D. (University & Swiss Federal Institute of Technology, Zürich, CH)
Adjunct Assistant Professor of Biomedical Engineering (Biomedical Engineering, Cleveland Clinic Foundation)

Kandice Kottke-Marchant, Ph.D., M.D. (Case Western Reserve University)
Adjunct Professor of Biomedical Engineering (Hematology, Cleveland Clinic Foundation)
Interaction of blood and materials

William Landis, Ph.D. (Massachusetts Institute of Technology)
Adjunct Professor of Biomedical Engineering (Department of Biochemistry and Molecular Pathology, Northeastern Ohio Universities College of Medicine)
Mineralization of vertebrates, effect of mechanical force on mineralization, calcium transport in mineralization, tissue engineering

Marc Penn, M.D., Ph.D. (Case Western Reserve University)
Adjunct Assistant Professor of Biomedical Engineering (Cardiology and Cell Biology, Cleveland Clinic Foundation)

Kimerly Powell, Ph.D. (Ohio State University)
Adjunct Associate Professor of Biomedical Engineering (Biomedical Engineering, Cleveland Clinic Foundation)
Image post-processing for detection and diagnosis of breast cancer and quantitative microscopy

Antonie J. van den Bogert, Ph.D. (University of Utrecht)
Adjunct Assistant Professor of Biomedican Engineering (Biomedical Engineering, Cleveland Clinic Foundation)

Ivan Vesely, Ph.D. (University of Western Ontario, Canada)
Adjunct Associate Professor of Biomedical Engineering (Biomedical Engineering, Cleveland Clinic Foundation)
Micromechanics of heart valves; fatigue of soft tissue

Geoffrey D.Vince, Ph.D. (University of Liverpool Medical School, United Kingdom)
Adjunct Assistant Professor of Biomedical Engineering (Biomedical Engineering, Cleveland Clinic Foundation)
Image and signal processing of intravascular ultrasound images, mechanics of coronary plaque rupture, cellular aspects of atherosclerosis

Michael Wendt, Ph.D. (University of Witten/Herdecke, Germany)
Adjunct Assistant Professor of Biomedical Engineering (Siemens Medical Solutions, USA, Inc.)
Interventional magnetic resonance imaging; wavelet encoding

Guang Yue, Ph.D. (University of Iowa)
Adjunct Assistant Professor of Biomedical Engineering (Biomedical Engineering, Cleveland Clinic Foundation)
Neural control of movement

Maciej Zborowski, Ph.D. (Polish Academy of Science)
Adjunct Assistant Professor of Biomedical Engineering (Biomedical Engineering, Cleveland Clinic Foundation)
Membrane separation of blood proteins

The Case Western Reserve undergraduate program leading to the Bachelor of Science degree with a major in biomedical engineering was established in 1972. The B.S. program in BME is accredited by the Accreditation Board of Engineering and Technology.

The educational objective of our undergraduate program is to develop in our students problem-solving skills, the ability to think independently, and the ability to assess ideas with an open mind, which will allow them to be successful as they go on in careers in biomedical engineering, to medical school, or to graduate school in biomedical engineering. Specifically, our goal is to develop in students the ability to:

Students, upon graduating from our program, should be:

Some B.S. graduates are employed in industry and medical centers. Others continue studies in biomedical engineering and other fields. Students with engineering ability and an interest in medicine may consider the undergraduate biomedical engineering program as an exciting alternative to conventional premedical programs. The undergraduate program has three major components (1) Engineering Core, (2) BME Core, and (3) BME Specialty Sequence. The Engineering Core provides a broad background in mathematics, sciences, and engineering. A typical program of study is shown in the table. The BME Core integrates engineering with biomedical science to solve biomedical problems. Hands-on experience in BME is developed through the undergraduate laboratory and project courses. In addition, by choosing a BME specialty sequence, the student can learn in depth about a specific area. This integrated program is designed to ensure that BME graduates are competent engineers. Students may select open electives for educational breadth or depth or to meet entrance requirements of medical school or other professional career choices. BME faculty serve as student advisors to guide students in choosing the program of study most appropriate for individual needs and interests.

Common BME specialties are biomaterials (orthopaedic, polymeric, tissue engineering), biomechanics (prosthetics and tissues), biomedical instrumentation (devices & sensors), biomedical computing and imaging, and biomedical systems & control. Courses for these specialties are presented in the table. Complete descriptions and suggested schedules for approved specialties are available on the department’s web page (bme.cwru.edu). These specialties provide the student with a solid background in a well-defined area of biomedical engineering. To meet specific educational needs, students may choose alternatives from among the suggested electives or design unique specialties subject to departmental guidelines and faculty approval.

Opportunities are available for students to alternate studies and work in industry as a co-op student, which is integrated in a 5-year program. Alternatively, students may obtain employment as summer interns.

A minor in biomedical engineering is offered to students who have taken the Engineering Core requirements. The minor consists of 15 credit hours based on two required courses, EMBE 201/EBME 202 and an approved set of three electives chosen from among EBME 303, EMBE 306, EBME 308, EBME 309/359, EBME 310/360, EBME 311, EBME 320, and EBME 324.

Undergraduates with a strong academic record may apply in their junior year for admission to the integrated B.S./M.S. program. A senior research project that begins in the summer after the junior year is designed to expand into an M.S. thesis. Also, the student begins to take graduate courses in the senior year. With continuous progress in research during three summers and the academic years, this program can lead to both the B.S. and M.S. in 5 years.

The objective of our graduate education program is to educate biomedical engineers for careers in industry, academia, health care, and government, and to advance research in biomedical engineering. The department provides a learning environment that encourages students to apply biomedical engineering methods to advance basic scientific discovery, integrate knowledge across the spectrum from basic cellular and molecular biology through tissue, organ, and whole body physiology and pathophysiology, and to exploit this knowledge to design diagnostic and therapeutic technologies that improve human health. The unique and rich medical, science, and engineering environment allows research projects ranging from basic science through engineering design and clinical application.

Numerous fellowships and research assistantships are available to support graduate students in their studies.

The M.S. program in biomedical engineering provides breadth in biomedical engineering and biomedical sciences with depth in an engineering specialty. In addition, students are expected to develop the ability to work independently on a biomedical research or design project. The M.S. requires a minimum of 30 credit hours. With an M.S. research thesis (Plan A), a minimum of 21 credits hours is needed in regular course work and 9 hours of thesis research (EBME 651). With an M.S. project (Plan B), a minimum of 27 credits hours is needed in regular course work, and three hours of project research (EBME 601).

Biomedical engineering students may apply for the Biomedical Entrepreneurship concentration in the Master of Engineering (MEM) program. The MEM is a joint degree offered by The Institute for the Integration of Management and Engineering (TIIME), in the Case School of Engineering and the Weatherhead School of Management. The objective of this program is to provide biomedical engineers with the business and management context required to enable them to drive innovation within biomedical companies while serving in a technical capacity.

Students can enter the program as undergradautes. The program does not interfere with undergradaute degree requirements. The curriculum inclues courses integrating engineering and management, as well as industrial internships. By making use of summers for both course work and internships, the degree is completed in one additional year beyond the B.S., for a total of five years.

Students should apply through TIIME.

For those students with primary interest in research, the Ph.D. in biomedical engineering provides additional depth and breadth in engineering and the biomedical sciences. Under faculty guidance, students are expected to undertake original research motivated by a biomedical problem. Research possibilities include the development of new theory, devices, or methods for diagnostic or therapeutic applications as well as for measurement and evaluation of basic biological mechanisms.

The Ph.D. program requires a minimum of 13 courses beyond the B.S. degree. There are four required core courses (EBME 403, 409, 451, 452). The balance of the courses can be chosen with significant flexibility to meet the career goals of the student, and to satisfy requirements of depth and breadth. Programs of study must include three graduate level courses in biomedical sciences and two courses whose content is primarily mathematical. Two semesters of departmental seminar attendance (EBME 611, 612) and three semesters of teaching experience (EBME 400T, 500T, 600T) are also required. Ph.D. programs of study are reviewed and must be accepted by the Graduate Education Committee and the department chairperson. Eighteen hours of EBME 701 registration are required.

Ph.D. candidacy requires passing certain milestones. A student is advanced to Ph.D. candidacy after passing the Ph.D. Qualifying Exam and obtaining approval of the Ph.D. short proposal. The Ph.D. is completed when the dissertation has been written and defended, and when at least two manuscripts have been submitted for publication and at least one of the two is accepted.

This program, which is administered through the School of Medicine is jointly sponsored with the Department of Physiology and Biophysics. A full description is available in the section on the School of Medicine.

This program, which is administered through the School of Medicine is jointly sponsored with the Department of Neurosciences. A full description is available in the section on the School of Medicine.

Students with outstanding qualifications may apply to either of two M.D./Ph.D. programs. Students interested in obtaining a combined M.D./Ph.D., with an emphasis on basic research in biomedical engineering, are strongly encouraged to explore the Medical Scientist Training Program (MSTP), administered by the School of Medicine. Alternatively, the Physician Engineer Training Program (PETP) was established to train future physicians who also possess expertise in state-of-the-art engineering medical technologies, with a research focus on applied biomedical engineering. The PETP is admiinstered through the BME Department. It is expected that graduates of the PETP will have a strong interest in the biomedical industrial sector, clinical medicine, or in academic positions in biomedical engineering, rather than the traditional M.D./Ph.D. career pathway in academic medicine.

Both M.D./Ph.D. programs require approximately 7-8 years of intensive study after the B.S.

Several research thrusts are available to accommodate various student backgrounds and interests. Strong research collaborations with clinical and basic science departments of the university and collaborating hospitals bring a broad range of opportunities, expertise, and perspective to student research projects.

Biomaterials/Tissue Engineering
Materials for implantation, including neural and cardiovascular tissue engineering, biomimetic materials, liposomal and controlled drug delivery, and biocompatible polymer surface modifications. Analysis of synthetic and biologic polymers by AFM, nanoscale structure-function relationships of orthopedic biomaterials.

Biomedical Image Processing and Analysis
MRI, PET, untrasound, optical coherence tomography, cardiac electrical potential mapping, human visual perception, image guided intervention.

Biomedical Sensing
Optical sensing, electrochemical and chemical fiber-optic sensors, chemical measurements in cells and tissues, endoscopy.

Cardiac Bioelectricity
Cardiac electrophysiology (at ion-channel, cell, and tissue levels), models of cellular activity, mechanisms of cardiac arrhythmias, optical imaging of electrical propagation in the heart, noninvasive electrocardiographic imaging.

Neural Engineering and Neural Prostheses
Neuronal mechanisms; neural interfacing for electric and magnetic stimulation and recording; neural dynamics, ion channels, second messengers, nitric oxide, signal processing in the retina; neural prostheses for control of limb movement, bladder, bowel, and respiratory function.

Transport and Metabolic Systems Engineering
Modeling and analysis of tissue responses to heating (tumor ablation, implanted artificial heart) and of cellular metabolism related to organ and whole-body function in health (exercise) and disease (cardiac).

The administrative offices of the Department of Biomedical Engineering are located in the Wickenden Building, which houses many BME research laboratories as well as the Center for Cardiovascular Biomaterials (CCB) and the Cardiac Bioelectricity Research and Training Center (CBRTC). Within the CCB are the laboratories for biomaterials microscopy, biopolymer & biomaterial interfaces, and molecular simulation. Other biomaterials related laboratories include Cell and Tissue Engineering and Biomaterials Protein Engineering. The CBRTC includes laboratories for High-Performance Cardiac Simulation and Display, Cardiac Cell Experiments, Cardiac Cell Imaging, and Cardiac Optical and Electrical Mapping. Optical laboratories deal with Microspectroscopic Diagnostics and Fiberoptic Biosensors. Diagnostic optical and electrochemical techniques are developed in the laboratory for Microchemical Sensors. The laboratory for Biomedical Image Processing and Analysis works on images from the molecular level to the tissue-organ level. Primary BME faculty are also directors of laboratories in other locations. The Endoscopy Research Laboratory is the center for work on Optical Computed Tomography. The Applied Neural Control Laboratory is a major facility for basic research and animal experimentation in the development of neural prostheses. The Neural Engineering Center and Laboratory is a major facility for basic research and animal experimentation. The focus is on recording and controlling neural activity to increase our understanding of the nervous system and to develop neural prostheses. The Functional Electrical Stimulation Center develops techniques for restoration of movement in paralysis, control of the nervous system, and implantable technology. Also, it promotes technology transfer and disseminates information about biomedical electrical stimulation. The Rehabilitation Engineering Center evaluates clinical functionality of neuroprostheses.

The department faculty and students have access to the facilities and major laboratories of the Case School of Engineering and of the School of Medicine. Faculty have numerous collaborations at University Hospitals, MetroHealth Medical Center, VA Medical Center, and the Cleveland Clinic Foundation. These provide extensive research resources in a clinical environment for both undergraduate and graduate students.

EBME 105. Introduction to Biomedical Engineering (3)
Biomedical engineering fields of activity. Research, development, and design for biomedical problems, diagnosis of disease, and therapeutic applications.

EBME 201. Physiology-Biophysics I (3)
Cell physiology. Electrophysiology of nerve and muscle. Motor system. Central nervous system. Sensory systems. Autonomic nervous system.

EBME 202. Physiology-Biophysics II (3)
Biological control systems. Cardiovascular, renal, respiratory, gastro-intestinal, and immune systems.

EBME 300. Dynamics of Biological Systems: A Quantitative Introduction to Biology (3)
(See BIOL 300.) Cross-listed as BIOL 300.

EBME 303. Structure of Biological Materials (3)
Structure of proteins, nucleic acids, connective tissue and bone from molecular to microscopic levels. Principles and applications of instruments for imaging, identification, and measurement of biological materials. Prereq: EBME 202. Cross-listed as EMAC 303.

EBME 306. Introduction to Biomedical Materials (3)
Applications of biomaterials in different tissue and organ systems. Relationship between physical and chemical structure of materials and biological system response. Choosing, fabricating and modifying materials for specific biomedical applications. Prereq: EBME 201 and EBME 202.

EBME 307. Biomechanical Prosthetic Systems (3)
Introduction to the basic biomechanics of human movement and applications to the design and evaluation of artificial devices intended to restore or improve movement lost due to injury or disease. Measurement techniques in movement biomechanics, including motion analysis, electromyography, and gait analysis. Design and use of upper and lower limb prostheses. Principles of neuroprostheses with applications to paralyzed upper and lower extremities.

EBME 308. Biomedical Signals and Systems (4)
Quantitative analysis of biomedical signals and physiological systems. System classification. Fourier and Laplace transforms. Frequency response of systems and circuits. A/D conversion, sampling, and discrete-time signal processing. Filter design. Laboratory and computational experiences with biomedical applications. Prereq: EBME 201, EBME 202, and ENGR 210.

EBME 309. Modeling of Biomedical Systems (3)
Mathematical modeling and computer simulation techniques with biomedical applications. Nonlinear dynamics and finite difference equations as applied to cellular and physiological systems. Theoretical models of excitable tissues (nerve and muscle). Application of electromagnetic field theory to bioelectric systems. Volume conductor fields generated by nerve, muscle, and cardiac excitation.

EBME 310. Principles of Biomedical Instrumentation (3)
Physical, chemical and biological principles for biomedical measurements. Modular blocks and system integration. Sensors for displacement, force, pressure, flow, temperature, biopotentials, chemical composition of body fluids and biomaterial characterization. Patient safety. Prereq: EBME 308.

EBME 311. Artificial Organs (3)
Engineering for replacement of kidney, lung, heart, and other organ functions. Chemical, electrical, mechanical, materials, pathological and surgical aspects. Prereq: EBME 202, EBME 308 and ENGR 210.

EBME 313. Biomedical Engineering Laboratory I (2)
Experiments for measurement, assisting, replacement, or control of various biomedical systems. Prereq: EBME 201, EBME 202 and ENGR 210. Coreq: ENGL 398N.

EBME 314. Biomedical Engineering Laboratory II (2)
Continuation of EBME 313. Prereq: EBME 201, EBME 202 and ENGR 210.

EBME 320. Medical Imaging Fundamentals (3)
Physical principles of medical imaging. Imaging devices for x-ray, ultrasound, magnetic resonance, etc. Image quality descriptions. Patient risk. Prereq: EBME 201, EBME 202, EBME 308, and EBME 310 or equivalent.

EBME 324. Laboratory Computing in Biomedical Engineering (3)
Hardware and software aspects of computer systems for laboratory application. Analog and digital interfacing. Signal conditioning and sampling requirements. Computer control of laboratory instruments and data acquisition. Biomedical applications. Prereq: EBME 201, EBME 202, and EBME 308.

EBME 350. Quantitative Molecular Bioengineering (3)
The teaching objective of this course is to equip the students with a "molecular toolbox"–a set of quantitative skills that permit intelligent designs of engineering solutions for medical problems at the molecular level. The core of the course will build on the physical and chemical principles in equilibrium, kinetics, and mass transport. Specific biomedical examples in bioengineering systems will be used throughout the course to illustrate the importance of understanding and application of these principles in problem solving. Prereq: ENGR 225.

EBME 359. Biomedical Computer Simulation Laboratory (1)
Computer simulation and mathematical models of biomedical systems. MATLAB software tools are used to demonstrate the basic properties of dynamical systems, numerical methods and their application to biomedical problems. Coreq: EBME 309.

EBME 360. Biomedical Instrumentation Laboratory (1)
A laboratory which focuses on the basic components of biomedical instrumentation and provides hands-on experience for students in EBME 310, Biomedical Instrumentation. The purpose of the course is to develop design skills and laboratory skills in analysis and circuit development. Coreq: EBME 310.

EBME 380. Design for Biomedical Engineers (3)
Design a useful product with potential commercial value. This course offers a design experience that builds on the fundamentals of Biomedical Engineering through the effective use of teams and team design. Prereq: EBME 310.

EBME 396. Special Topics in Undergraduate Biomedical Engineering I (1-18)
(Credit as arranged.) Prereq: Consent of instructor.

EBME 400T. Graduate Teaching I (0)
This will provide the Ph.D. candidate with experience in teaching undergraduate or graduate students. The experience is expected to consist of direct student contact, but will be based upon the specific departmental needs and teaching obligations. This teaching experience will be conducted under the supervision of the faculty member who is responsible for the course, but the academic advisor will assess the educational plan to ensure that it provides an educational opportunity for the student. Students in this course may be expected to perform both contact (C) and non-contact (NC) teaching in this course sequence. Examples are: develop teaching or lecture materials (NC); run recitation groups (C); provide laboratory assistance (C) or (NC); present individual lectures (C); tutor (C); prepare and grade exams/quizzes/homework (NC). Prereq: Ph.D. student in Biomedical Engineering.

EBME 402. Muscles, Biomechanics, and Control of Movement (4)
Quantitative and qualitative descriptions of the action of muscles in relation to human movement. Introduction to rigid body dynamics and dynamics of multi-link systems using Newtonian and Lagrangian approaches. Muscle models with application to control of multi-joint movement. Forward and inverse dynamics of multi-joint, muscle driven systems. Dissection, observation and recitation in the anatomy laboratory with supplemental lectures concentrating on kinesiology and muscle function. Prereq: EMAE 181 or equivalent. Cross-listed as EMAE 402.

EBME 403. Biomedical Transducers (3)
Analysis and design of transducers: optical, photo-electric, electrochemical, electrical, mechanical, electromechanical, and thermoelectric. Applications to biomedical systems. Prereq: EBME 310 and EBME 360 or consent of instructor.

EBME 405. Materials for Prosthetics and Orthotics (3)
Fundamental concepts of metallic and ceramic materials. Wear, corrosion, and failure of implants. Properties of hard tissues and joints. Characterization of biomaterials. Biocompatibility of materials. Orthopaedic and dental applications. Prereq: EBME 306.

EBME 406. Polymers in Medicine (3)
Distribution of plastic implants in the body, including history and statistics; chemical and physical characteristics of biomedical polymers, including general implant requirements, reactions of the host to implants, reactions of implants to physiological conditions, physiological and biomechanical basis for soft-tissue implants; plastic materials used in medicine and surgery; frontiers in biomedical polymers (current topics directed to the design and development of new biomedical polymers). Prereq: Consent of instructor. Cross-listed as EMAC 471.

EBME 407. Applied Neural Control (3)
Fundamental concepts related to electrical stimulation of the nervous system. Cable equation, currents in volume conductors, electrical models of axons, interaction between axons and electrical fields, tissue damage of electrical stimulation, electrochemistry of electrical stimulation, electrodes for electrical stimulation, applications to neuromuscular, sensory, and other physiological systems. Prereq: EBME 451 and EBME 409.

EBME 408. Tissue and Cellular Engineering (3)
Tissue engineering approach for augmentation or replacement of compromised tissue function in nerve, microvessels, skin and cartilage. Integrative exploration of the use of three-dimensional polymeric scaffolds and drug delivery vehicles, and gene therapy and cellular engineering for functional repair of injured tissues. Prereq: Consent of instructor.

EBME 409. Systems and Signals in Biomedical Engineering (3)
Modeling concepts (probability, kinetics, mass transport, parameter estimation); dynamic systems (nonlinear, lumped, distributed, Laplace transform, matrices, eigenvalues, linearization, stability, phase-plane); signal analysis (continuous and discrete, time and frequency domains, spectral representation, Fourier analysis, data sampling, noise analysis, filtering, aliasing); numerical methods (initial-value problems, finite differences, Fourier transforms, matrix operations, nonlinear estimation, image processing, power spectrum analysis, MATLAB implementation). Prereq: EBME 308 or equivalent.

EBME 410. Medical Imaging Fundamentals (3)
Physical principles of medical imaging. Imaging devices for x-ray, ultrasound, magnetic resonance, etc. Image quality descriptions. Patient risk. Prereq: EBME 308 and EBME 310 or equivalent.

EBME 411. Artificial Organs (3)
Engineering for replacement or augmentation of tissues (e.g., nerve or vascular) and organs (e.g., kidney and heart). Chemical, electrical, mechanical, materials, pathological and surgical aspects. Prereq: EBME 451 and EBME 452.

EBME 412. Biomedical Signal Processing (3)
Application of digital processing techniques to biomedical signals. Spectra and digital filters. Processing evoked responses. Electrocardiograms, electroencephalograms, and other applications. Prereq: EBME 409.

EBME 414. Laboratory Computing in Biomedical Engineering (3)
Hardware and software aspects of computer systems for laboratory application. Analog and digital interfacing. Signal conditioning and sample requirements. Computer control of laboratory instruments and data acquisition. Biomedical applications. Prereq: EBME 308 or equivalent.

EBME 416. Biomaterials in Drug Delivery (3)
Fundamental principles in design and engineering of molecular architectures of biomaterials for biomedical applications. Structure-function relationships at the molecular level. Tailoring the surface and bulk structures for applications in drug delivery, tissue engineering, and biomedical imaging. Prereq: EBME 303 or EMAC 303. Coreq: EBME 306.

EBME 417. Structure and Function of Excitable Cells (3)
Ion channels are the molecular basis of membrane excitability in all cell types, including neuronal, heart, and muscle cells. This course presents the structure and the mechanism of function of ion channels at the molecular level. It introduces the basic principles and methods in the ion channel study including the ionic basis of membrane excitability, thermodynamic and kinetic analysis of channel function, voltage clamp and patch clamp techniques, and molecular and structural biology approaches. The course will cover structure of various potassium, calcium, sodium, and chloride channels and their physiological function in neural, cardiac, and muscle cells. Exemplary channels that have been best studied will be discussed to illustrate the current understanding of the molecular mechanisms of channel gating and permeation. Prereq: Consent of instructor.

EBME 418. Electronics for Biomedical Engineering (3)
Review of electronic circuits. Analog design for biomedical electronics. Low noise, precision amplification, shielding, grounding, interfacing, and electrical safety. Electrophysiological amplifiers and biomagnetic field measurements. Prereq: EBME 308.

EBME 427. Movement Biomechanics and Rehabilitation (3)
Introduction to the basic biomechanics of human movement and applications to the design and evaluation of artificial devices intended to restore or improve movement lost due to injury or disease. Measurement techniques in movement biomechanics, including motion analysis, electromyography, and gait analysis. Design and use of upper and lower limb prostheses. Principles of neuroprostheses with applications to paralyzed upper and lower extremities. Term paper required. Prereq: Consent of instructor.

EBME 431. Physics of Imaging (3)
Description of physical principles underlying the spin behavior in MR and Fourier imaging in multi-dimensions. Introduction of conventional, fast, and chemical-shift imaging techniques. Spin echo, gradient echo, and variable flip-angle methods. Projection reconstruction and sampling theorems. Bloch equations, T1 and T2 relaxation times, RF penetration, diffusion and perfusion. Flow imaging, MR angiography, and functional brain imaging. Sequence and coil design. Prerequisite may be waived with consent of instructor. Prereq: PHYS 122 or PHYS 124 or EBME 410. Cross-listed as PHYS 431.

EBME 447. Rehabilitation for Scientists and Engineers (3)
Medical, psychological, and social issues influencing the rehabilitation of people with spinal cord injury, stroke, traumatic brain injury, and limb amputation. Epidemiology, anatomy, pathophysiology and natural history of these disorders, and the consequences of these conditions with respect to impairment, disability, handicap and quality of life. Students will directly observe the care of patients in each of these diagnostic groups throughout the full continuum of care starting from the acute medical and surgical interventions to acute and subacute rehabilitation, outpatient medical and rehabilitation management and finally to community re-entry. Prereq: Consent of department.

EBME 451. Physiological Processes I (3)
Cell and molecular biology. Nerve and muscle function. Motor systems and feedback control. Autonomic system mechanisms. Brain and sensory systems.

EBME 452. Physiological Processes II (3)
Heart and vascular system. Respiratory, renal, and regulatory systems. Gastro-intestinal system and metabolism. Prereq: Consent of instructor.

EBME 460. Advanced Topics in NMR Imaging (3)
Frontier issues in understanding the practical aspects of NMR imaging. Theoretical descriptions are accompanied by specific examples of pulse sequences, and basic engineering considerations in MRI system design. Emphasis is placed on implications and trade-offs in MRI pulse sequence design from real-world versus theoretical perspectives. Prereq: EBME 431 or PHYS 431. Cross-listed as PHYS 460.

EBME 461. Biomedical Image Processing and Analysis (3)
Principles of image processing and analysis with applications to biomedical images from the nano-scale to 3D whole organ imaging. Topics include image filtering, enhancement, restoration, registration, morphological processing, and segmentation. Prereq: EBME 409 or equivalent.

EBME 478. Computational Neuroscience (3)
Computer simulation of neurons and neural circuits, and the computational properties of nervous systems. Students are taught a range of models for neurons and neural circuits, and are asked to implement and explore the computational and dynamic properties of these models. The course introduces students to dynamical systems theory for the analysis of neurons and neural circuits, as well as to cable theory, passive and active compartmental modeling, numerical integration methods, models of plasticity and learning, models of brain systems, and their relationship to artificial neural networks. Term project required. Two lectures per week. Cross-listed as EECS 478.

EBME 479. Seminar in Computational Neuroscience (3)
Readings and discussion in the recent literature on computational neuroscience, adaptive behavior, and other current topics. Cross-listed as BIOL 479.

EBME 500T. Graduate Teaching II (0)
This course will provide the Ph.D. candidate with experience in teaching undergraduate or graduate students. The experience is expected to consist of direct student contact, but will be based upon the specific departmental needs and teaching obligations. This teaching experience will be conducted under the supervision of the faculty member who is responsible for the course, but the academic advisor will assess the educational plan to ensure that it provides an educational opportunity for the student. Students in this course may be expected to perform both contact (C) and non-contact (NC) teaching in this course sequence. Examples are: develop teaching or lecture materials (NC); run recitation groups (C); provide laboratory assistance (C) or (NC); present individual lectures (C), tutor (C); prepare and grade exams/quizzes/homework (NC). Prereq: Ph.D. student in Biomedical Engineering.

EBME 501. Bioelectric Phenomena (3)
Models of excitable cells and membranes. Cardiac action potentials and propagation of excitation. Bioelectric sources, volume conductor fields, and inverse problems. Prereq: EBME 451 and EBME 409.

EBME 502. Cardiac Excitation, Rhythm, and Control (3)
Cardiac excitation: sub-cellular and cellular. Inter-cellular communication. Propagation of the cardiac electrical potential. Arrhythmias. Neural control of the heart. Vagal nerve stimulation. Neurotransmitters and neuropeptides. Prereq: EBME 501.

EBME 503. Biomolecular Forces (3)
Advanced course on the theory, measurement, and analysis of the intermolecular physical forces that dominate cell and molecular interactions in dynamic aqueous systems. The aim of this course is to provide students involved in biomaterials engineering and studies on cell and molecular interactions with (i) a quantitative and fundamental understanding of the intermolecular forces (electrostatic, van der Walls, solvation forces) that direct cell and molecular adhesion, self-assembling systems (bilayers, cell membranes) and specific and non-specific receptor-ligand binding; (ii) the ability to develop mechanistic models for surface adhesion, self-assembly, cell surface binding and signal transduction; and (iii) skills for measurement and quantitative analysis of forces (nano- to pico-Newton levels) in the "near-surface" (1-10 nm) domain by atomic force microscopy and related force measurement techniques. Prereq: EBME 405 or EBME 406, undergraduate electricity and magnetism, undergraduate physical chemistry, or consent of instructor.

EBME 504. Transport Processes of Biomedical Systems (3)
Mass and heat transport processes. Metabolic processes. Spatially lumped and distributed models of organs, tissues and cells. Numerical methods for computer simulation. Applications to cells, tissues, and organs. Prereq: EBME 409.

EBME 507. Motor System Neuroprostheses (3)
Design and implementation of neuroprostheses. Transformation of muscle action into limb movement. Musculoskeletal modeling and simulation. Control of the musculoskeletal system by neural stimulation. Prereq: Consent of instructor.

EBME 511. Nonlinear Wavefront Dynamics in Cardiac Bioelectricity (3)
Mathematical and descriptive analysis of atrial fibrillation and flutter and various types of action potential reentry. Specific aspects include phase resetting, electrical restitution and alternans generation, conduction velocity variation, spiral wave propagating patterns and stability, and propagation failure. Computer models will be used to illustrate the concepts with simulations related to the physiology, diagnosis, and treatment of abnormal cardiac rhythm. Prereq: EBME 409.

EBME 513. Biomedical Optical Diagnostics (3)
Engineering design principles of optical instrumentation for medical diagnostics. Elastic and inelastic light scattering theory and biomedical applications. Confocal and multiphoton microscopy. Light propagation and optical tomographic imaging in biological tissues. Design of minimally invasive spectroscopic diagnostics. Prereq: EBME 403 or PHYS 326 or consent.

EBME 517. Quantitative Neurophysiology (3)
This course provides a unique opportunity to gain advanced knowledge in the area of neurophysiology, neuroscience, and cellular biophysics/physiology from the quantitative point of view. The instructors are from different departments which will give students the rare opportunity to learn and understand the material from various angles. The mathematical load varies depending on the topic, however the familiarity with or willingness and ability to learn basic important mathematical concepts such as differentiation, probability, or matrices is essential. The course will start by studying the laws of physics that govern the behavior of ions in biological solutions and near the cell membrane. The next part of the course deals with the voltage-gated ion channels of the excitable cell: activity, structure, functions, and models. The third part is devoted to modeling electrical activity of a neuron. The fourth part describes the synaptic interaction between neurons, from presynaptic calcium dynamics to postsynaptic membrane and ligand-gated channels. The last part applies the acquired knowledge to understanding a neuronal network (hippocampus). Along with the lectures, the students will prepare a model of the neuron using the NEURON software. This project will be in constant development during the course, i.e., the complexity of the model will increase as long as new material is learned. Prereq: MATH 224, EBME 451, or BIOL 373/473, or permission of department.

EBME 519. Parameter Estimation for Biomedical Systems (3)
Linear and nonlinear parameter estimation of static and dynamic models. Identifiability and parameter sensitivity analysis. Statistical and optimization methods. Design of optimal experiments. Applications to cells, tissues, and organs. Prereq: EBME 409 or consent of instructor.

EBME 523. Chemical and Optical Sensors (3)
Fundamental electrical, electrochemical, and optical measurement techniques. Sensitive and selective biological membranes based on ion, enzyme, and immuno-reactions. Sensor stability and response time. Prereq: EBME 403.

EBME 550. Neuromechanics Seminar (0)
Current research in neuromechanical systems, including movement control in natural organisms, biologically inspired robots, and hybrid (artificial/natural) neural prosthetic systems. Presentations by students, faculty, and visiting scholars. Cross-listed as BIOL 550, EECS 550, and EMAE 550.

EBME 600T. Graduate Teaching III (0)
This course will provide the Ph.D. candidate with experience in teaching undergraduate or graduate students. The experience is expected to consist of direct student contact, but will be based upon the specific departmental needs and teaching obligations. This teaching experience will be conducted under the supervision of the faculty member who is responsible for the course, but the academic advisor will assess the educational plan to ensure that it provides an educational opportunity for the student. Students in this course may be expected to perform both contact (C) and non-contact (NC) teaching in this course sequence. Examples are: develop teaching or lecture materials (NC); run recitation groups (C); provide laboratory assistance (C) or (NC); present individual lectures (C); tutor (C); prepare and grade exams/quizzes/homework (NC). Prereq: Ph.D. student in Biomedical Engineering.

EBME 602. Special Topics (1-18)
Prereq: Consent of instructor.

EBME 611. BME Departmental Seminar I (0)
Required of all first-year graduate students in BME.

EBME 612. BME Departmental Seminar II (0)
Continuation of EBME Departmental Seminar I. Required of all first-year graduate students in BME.

EBME 621. BME Research Rotation I (0)
Opportunity for trainees to participate in BME research under supervision of faculty.

EBME 622. BME Research Rotation II (0)
Opportunity for trainees to participate in BME research under supervision of faculty.

EBME 701. Dissertation Ph.D. (1-18)
Ph.D. candidates only.

To ensure depth in a particular area, students take one of the seven specialty sequences listed below. Students should consult the website of the Department of Biomedical Engineering to learn more about the educational program and to determine the best order for taking courses in a particular sequence.

Biomechanics
EMAE 181, ECIV 310, EMAE 250, EMAE 271, and EMAE 372; and technical electives from EBME 307, EBME 311, EBME 324, EBME 402, EMAE 377, EMAE 350, EBME 307, EMAE 415, EMAE 370

Biomaterials (polymeric)
EMAC 270, CHEM 223, EMAC 351, and EBME 303; and technical electives from EBME 416, EBME 405, EMAC 377, ECHE 360, EBME 311, EMAC 376, EBME 406, EBME 408, EMAC 276, and EMAC 352, EMAC 351, and EMAC 377.

Biomaterials (orthapedic)
EMSE 201, ECIV 310, EMSE 303, and EMAC 270; and technical electives from EBME 405, EMSE 316, EBME 416, EMSE 202, EMSE 270, EMSE 313, EMSE 411, EMAE 372, EMAC 276, EMAC 250, EBME 303, EBME 311, EBME 406, EBME 408, EMAE 415

Biomaterials (Tissue Engineering)
CHEM 223, ECHE 360, EMAC 270, and ECHE 340; and technical electives such as EBME 405, EBME 416, EMAC 377, BIOC 307, CBIO 453, EBME 406, EBME 408, ECHE 364, EMAC 376, BIOC 308, and EBME 303.

Biomedical Computing & Imaging
ECES 233, ECES 337, and EBME 320; and technical electives from ECES 281, EBME 431, ECES 375, EBME 324, ECES 340, ECES 391, MIDS 329, EBME 461, ECES 375, ECES 341, ECES 338, and MATH 304

Biomedical Instrumentation (devices)
ECES 245, ECES 281, and ECES 344; and technical electives from EEAP 382, EEAP 309, ECES 313, EBME 403, EBME 320, EBME 324, ECES 321, ECES 311, EBME 418, PHYS 326, ECES 282, ECES 322, ECES 344, ECHE 370, ECHE 380, and ECHE 381.

Biomedical Systems & Control
ECES 304, ECES 313, ECES 322, and EMAE 181; and technical electives ECES 306, MATH 201, EBME 324, OPRE 345, EBME 402, EBME 407, EBME 320, MATH 201, OPRE 345, EBME 461, EMBE 307, and ECES 346.

Notes
This gives 129 credits. Varies from sequence to sequence.

The profession of chemical engineering involves the analysis, design, operation and control of processes that convert matter and energy to more useful forms, encompassing processes at all scales from the molecular to the megascale. Traditionally, chemical engineers are responsible for the production of basic chemicals, plastics, and fibers. However, today’s chemical engineers are also involved in food and fertilizer production, synthesis of electronic materials, waste recycling, and power generation. Chemical engineers also develop new materials (ceramic composites and electronic chips, for example) as well as biochemicals and pharmaceuticals. The breadth of training in engineering and the sciences gives chemical engineers a particularly wide spectrum of career opportunities. Chemical engineers work in the chemical and materials related industries, in government, and are readily accepted by graduate schools in engineering, chemistry, medicine, and law (mainly for patent law). The Bachelor of Science degree is accredited by the Engineering Accreditation Commission of the Accreditation Board for Engineering and Technology.

The department offers Bachelor of Science in Engineering, Master of Science, and Doctor of Philosophy degree programs that provide preparation for work in all areas of chemical engineering. Breadth sequences in biochemical engineering, biomedical engineering, computing, electrochemical engineering, electronic materials, environmental engineering, management/entrepreneurship, polymer science, systems and control, or advanced studies provide depth and specialization for undergraduates majoring in chemical engineering. In addition, for students with a strong interest in polymer engineering, a minor in macromolecular science can be integrated with the chemical engineering curriculum. Chemical engineering undergraduates are members of the student chapter of the American Institute of Chemical Engineers (AIChE). The AIChE chapter sponsors social events, field trips to local industry, technical presentations by outside speakers, and employment counseling. Information about the AIChE can be obtained through the department, the chapter president or the chapter advisor. There are fifteen full-time faculty members, all of whom are pursuing active research programs. The research of the faculty is aimed at advanced and cutting-edge areas of chemical engineering.

Peter N. Pintauro, Ph.D. (University of California, Los Angeles)
Professor and Department Chair
Electrochemical engineering, membrane fabrication, modeling transport in ion-exchange membrane, organic elecrochemical synthesis, fuel cells

John C. Angus, Ph.D. (University of Michigan)
Kent Hale Smith Professor of Engineering
Chemical vapor deposition of diamond, electrochemistry of diamond gallium nitride synthesis

Harihara Baskaran, Ph.D. (The Pennsylvania State University)
Assistant Professor
Transport Phenomena in Biology and Medicine

Robert V. Edwards, Ph.D. (Johns Hopkins University)
Professor
Laser anemometry, mathematical modeling, data acquisition

Donald L. Feke, Ph.D. (Princeton University)
Professor and Interim Associate Provost for Planning and Assessment.
Colloidal phenomena, dispersive mixing, fine particle processing

Nelson C. Gardner, Ph.D. (Iowa State University)
Associate Professor
High-gravity separations, sulfur removal processes

Jeffrey T. Glass, Ph.D. (University of Virginia), M.B.A. (Duke University)
Joseph S. Toot Professor of Engineering
Plasma processing and materials characterization of thin films, measurement of device properties

Howard L. Greene, Ph.D. (Cornell University)
Principal Researcher
Catalysis and reactor design

Robert E. Harris, Ph.D. (Northeastern University), M.B.A. (Case Western Reserve University)
Adjunct Professor of Engineering
Process design, process synthesis, analysis, design and simulation

Uziel Landau, Ph.D. (University of California, Berkeley)
Professor
Electrochemical engineering, modeling of electrochemical systems, electrodeposition, batteries and fuel cells

Chung-Chiun Liu, Ph.D. (Case Institute of Technology)
Wallace R. Persons Professor of Sensor Technology & Control
Electrochemical sensors, electrochemical synthesis, electrochemistry related to electronic materials

J. Adin Mann, Jr., Ph.D. (Iowa State University)
Professor
Surface phenomena, interfacial dynamics, colloid science, light scattering, biomemetics, molecular electronics

Heidi B. Martin, Ph.D. (Case Western Reserve University)
Nord Assistant Professor of Engineering
Conductive Diamond Films; Electrochemical Sensors; Chemical Modification of Surfaces for Electrochemical and Biomedical Applications; Biomaterials; Microfabrication of Sensors and Devices

Philip W. Morrison, Jr., Ph.D. (University of California, Berkeley)
Associate Professor
Materials synthesis, in-situ diagnostics of thin film and particle formation processes

Syed Qutubuddin, Ph.D. (Carnegie Mellon University)
Professor
Surfactant and polymer solutions, separations, nanoparticles, novel polymeric materials, nanocomposites

Robert F. Savinell, Ph.D. (University of Pittsburgh)
George S. Dively Professor and Dean of Engineering
Electrochemical engineering, electrochemical reactor design and simulation, electrode processes, batteries and fuel cells

Thomas A Zawodzinski, Ph.D. (State University of New York at Buffalo)
Ohio Eminent Scholar in Fuel Cells and F. Alex Nason Professor of Engineering
Fuel cells, transport and electrochemistry in energy conversion and storage devices, NMR spectroscopy and imaging, transport/structure property relationships in polymer electrolytes, self-assembly chemistry

The Case School of Engineering prepares and challenges its students to take leadership positions in engineering and computer science. The increasing role of technology in virtually every facet of our culture – communications, transportation, construction, health care, the environment, and even our system of wealth distribution – makes it vital that engineering- oriented students have access to progressive and cutting-edge programs stressing the following five areas of excellence:

The Chemical Engineering Department expands these more general objectives as follows:

A distinctive feature of the chemical engineering program is the three-course breadth elective sequence taken during the junior and senior years that permits a student to major in chemical engineering and, at the same time, pursue an interest in a related field. Nine elective sequences have standing departmental approval: biochemical engineering, biomedical engineering, computing, electrochemical engineering, electronic materials, environmental engineering, management/entrepreneurship, polymer science, and systems and control. There is also an advanced study sequence for combined B.S./M.S. students.

For students wanting to pursue an interest in polymers, but major in chemical engineering, two five-course minor sequences, Polymer Processing and Characterization, and Polymer Production are available.

Polymer Processing and Characterization
EMAC 270, Introduction to Polymer Science (F, Sp)

EMAC 376, Polymer Engineering (F, Sp)

EMAC 377, Polymer Processing (F)

EMAC 372, Polymer Processing and Testing Laboratory (Sp)

EMAC 575, Polymer Rheology

Polymer Production
EMAC 270, Introduction to Polymer Science (F,Sp)

EMAC 272, Polymer Analysis Laboratory (Sp)

EMAC 276, Polymer Properties and Design (Sp)

EMAC 378, Polymer Production and Technology (Sp)

EMAC 398, Polymer Sci. & Engr. Project (F, Sp)

A minor sequence in chemical engineering is available for students majoring in engineering, chemistry, or physics. A minimum of 15 credits must be completed, and must include

ECHE 260 Introduction to Chemical Systems

ENGR 225 Thermodynamics, Fluid Mechanics, Heat and Mass Transfer (F,Sp)

ECHE 360 Transport Phenomena for Chemical Systems (F)

and any two of the following

ECHE 361 Separation Processes (Sp)

ECHE 363 Thermodynamics of Chemical Systems (Sp)

ECHE 364 Chemical Reaction Processes (Sp)

ECHE 365 Measurements Laboratory (Sp)

ECHE 367 Process Control (F)

This program offers outstanding undergraduate students the opportunity to obtain an M.S. degree, with a thesis, in one additional year of study beyond the B.S. degree. (Normally, it takes 2 years beyond the B.S. to earn an M.S. degree.) In this program, an undergraduate student can take up to nine hours of graduate credit that simultaneously satisfies undergraduate requirements. Typically, students in this program start their research leading to the M.S. thesis in the fall semester of the senior year. The department endeavors to support such students through the following summer and academic year at the normal stipend for entering graduate students. The B.S. degree is awarded at the completion of the senior year. Application for admission to the five year B.S./M.S. program is made after completion of five semesters of course work. Minimum requirements are a 3.2 grade point average and the recommendation of the department.

The cooperative bachelor’s/master’s program enables outstanding students who are enrolled in the cooperative program to earn an M.S. in one semester beyond the B.S. degree. Students complete six credits of a graduate project (ECHE 660) during the second co-op period and follow an Advanced Study elective sequence. The courses ECHE 460, ECHE 461, and an agreed-upon mathematics course are used to satisfy both graduate and undergraduate requirements. At the end of the fifth year, the student receives the B.S. degree. Upon completion of an additional 12 credits of graduate work the following semester, the student receives the M.S. degree (non-thesis). Application for admission to the five-and a-half-year co-op B.S./M.S. program is made during the second semester of the junior year (this semester is taken in the fall of the fourth year). Minimum requirements are a 3.2 grade point average, good performance in the previous co-op assignment, and the recommendation of the department.

Each M.S. candidate must complete a minimum of 27 hours of graduate-level credits. These credits can be distributed in one of two ways.

Plan A.
Students electing Plan A take 19 hours of graduate-level course work (six courses plus ECHE 401, Chemical Engineering Communications) and complete at least 9 credit hours of M.S. thesis research.

Plan B.
Part-time students, and those in the 5-1/2-year B.S./M.S. cooperative program, may opt for Plan B, which requires completion of 24 credit hours (eight courses) of approved graduate course work and a 3 credit hour project replacing the M.S. thesis. In special cases, a student may be permitted to complete a 6 credit project. In this case only seven courses will be required.

All M.S. students are required to take the following courses: ECHE 460, Thermodynamics of Chemical Systems (3) ; ECHE 461, Transport Phenomena (3) ; ECHE 462, Chemical Reaction Engineering (3) ; and ECHE 475, Chemical Engineering Analysis (3) or an equivalent graduate-level math course. The other courses should be technical graduate-level courses selected after consultation with the advisor. In special circumstances, e.g., students have taken a similar or complementary course at another university, one of the required courses may be waived from the Program of Study. All full-time M.S. students are expected to do some teaching as part of their education. Also, at various points during their thesis research, students will be required to present seminars and reports on their progress.

The Department of Chemical Engineering also participates in the practice-oriented Master of Engineering program offered by the Case School of Engineering. In this program, students complete a core program. The Department of Chemical Engineering participates in the Chemical and Materials Processing and Synthesis sequence.

The degree of Doctor of Philosophy is awarded in recognition of deep and detailed knowledge of chemical engineering and comprehensive understanding of related subjects together with a demonstration of the ability to perform independent investigations, to suggest new areas for research, and to communicate results in an acceptable manner. The minimum course requirements for the Ph.D. degree in chemical engineering are as follows:

Depth Courses
All programs of study must include ECHE 401, Chemical Engineering Communications (1), ECHE 460, Thermodynamics (3), ECHE 461, Transport Phenomena (3), and ECHE 462, Chemical Reaction Engineering (3), plus a minimum of three other chemical engineering courses.

Breadth and Basic Science Courses
A minimum of six courses outside the department must be taken. These can be chosen from other engineering departments and the departments of mathematics, chemistry, physics, biology, and geological sciences. A minimum of two elective courses must be in mathematics.

Comments on Ph.D. Guideline
The department anticipates that from time to time special cases will arise which are exceptions to the above guidelines, e.g., a student may have taken a graduate-level thermodynamics course at another school. In these cases, the student must attach a statement to the program of study justifying the departure from the guidelines. It should be noted that the above guidelines are a minimum requirement. Only in rare circumstances will programs of study be approved with only 12 courses (36 credit hours). A total of 15 courses (45 credit hours) is typical for the Ph.D. degree. It is expected that the elective courses will form a coherent whole with a concentration in one area, e.g., systems, polymers, surface science, etc., rather than a smattering of introductory courses in many diverse subjects. All programs are chosen with the approval of the student’s faculty advisor.

Other Requirements for the Ph.D. Degree
Students who wish to enter the Ph.D. program must pass a general examination covering material through the beginning graduate level courses. A thesis proposal and an independently generated proposal are also required. All Ph.D. students must satisfy the residency requirements of the university and the Case School of Engineering. Some teaching is also required. In addition, at various points in the course of the dissertation research, students will be required to prepare reports and seminars on their work, and defend their dissertation. The Chemical Engineering Graduate Student Handbook contains a more detailed description of the department’s Ph.D. requirements and a time schedule for their completion.

The research in the department is sponsored by a variety of state and federal agencies, by private industry, and by foundations. current active rsarch topic include:

The department is housed in the Albert W. Smith Building on the Case Quadrangle. Professor Smith was chair of industrial chemistry at Case from 1911 to 1927. Under his leadership a separate course of study in chemical engineering was introduced at Case in 1913. Professor Smith was also a close associate of Herbert Dow, the Case alumnus who founded Dow Chemical in 1890 with the help and support of Professor Smith. The Albert W. Smith Chemical Engineering Building contains two classrooms, one designed for computer and television instruction; the undergraduate Unit Operations Laboratory; a high bay area for process-related research; reinforced concrete, vertically vented chamber for hazardous and high-pressure research; a constant temperature and humidity room; an instrument room; and the normal complement of offices and research laboratories. The department has unusually strong facilities for electrochemical and fuel cell research, for microfabrication, and for chemical vapor deposition and thin film synthesis. In addition, a full range of biochemical, analytical and materials characterization instrumentation is available in the Case School of Engineering. Analytical instrumentation is available within the Department of Chemical Engineering, the Department of Chemistry, and the Materials Research Laboratory.

ECHE C100. Co-op Seminar I for Chemical Engineering (1)
Professional development activities for students returning from cooperative education assignments. Prereq: COOP 001.

ECHE C200. Co-op Seminar II for Chemical Engineering (2)
Professional development activities for students returning from cooperative education assignments. Prereq: COOP 002 and ECHE C100.

ECHE 151. Introduction to Chemical Engineering at Case (0)
Introduction to the Chemical Engineering Department and its activities: faculty and faculty research areas, breadth elective sequences, cooperative education, Summer Lab in London, Junior Year in Edinburgh, industrial employment opportunities, non-traditional employment opportunities. Required of Chemical Engineering students before their junior year.

ECHE 250. Honors Research I (1-3)
A special program which affords students the opportunity to conduct research under the guidance of one of the faculty. At the end of the first semester of the sophomore year, students who have a strong interest in research are encouraged to discuss research possibilities with the faculty. Assignments are made based on mutual interest. Subject to the availability of funds, the faculty employs students through the summers of their sophomore and junior years, as members of their research teams.

ECHE 251. Honors Research II (1-3)
(See ECHE 250.) Prereq: ECHE 250.

ECHE 260. Introduction to Chemical Systems (3)
Material and energy balances. Conservation principles and the elementary laws of physical chemistry applied to chemical processes. Developing skills in quantitative formulation and solution of word problems.

ECHE 340. Biochemical Engineering (3)
Chemical engineering principles applied to biological and biochemical systems and related processes. Microbiology and biochemistry linked with transport phenomena, kinetics, reactor design and analysis, and separations. Specific examples of microbial and enzyme processes of industrial significance. Prereq: BIOC 307 and BIOL 343 and ECHE 364.

ECHE 360. Transport Phenomena for Chemical Systems (4)
Viscous and turbulent fluid flow; heat and mass transport. Microscopic and macroscopic transport of mass, momentum, and energy including conduction and convection as well as interfacial and radiative heat transport. Design of piping networks, pumps, packed/fluidized beds, and heat exchangers. Diffusion and interfacial mass transfer. Heat and mass transfer analogies. Vector/tensor analysis and dimensional analysis used throughout. Prereq: MATH 223 and ENGR 225.

ECHE 361. Separation Processes (3)
Analysis and design of separation processes involving distillation, extraction, absorption, adsorption, and membrane processes. Design problems and the physical and chemical processes involved in separation. Equilibrium stage, degrees of freedom in design, graphical and analytical design techniques, efficiency and capacity of separation processes. Prereq: ECHE 260 and ECHE 363.

ECHE 362. Chemical Engineering Laboratory (4)
Experiments in the operation of separation and reaction equipment, including design of experiments, technical analysis, and economic analysis. Experiments cover distillation, liquid-liquid extraction, heat transfer, fluidized beds, control, membrane separations, and chemical and electrochemical reactors. Prereq: ECHE 360, ECHE 361, ECHE 363, and ECHE 364.

ECHE 362L. Chemical Engineering Laboratory in London (4)
A version of ECHE 362 taught during the summer at University College of London. Prereq: ECHE 360, ECHE 363, and ECHE 364.

ECHE 363. Thermodynamics of Chemical Systems (3)
First law, second law, phase equilibria, phase rule, chemical reaction equilibria, and applications to engineering problems. Thermodynamic properties of real substances, with emphasis on solutions. Thermodynamic analysis of processes including chemical reactions. Prereq: ECHE 260 and ENGR 225. Coreq: MATH 224.

ECHE 364. Chemical Reaction Processes (3)
Design of homogeneous and heterogeneous chemical reactor systems. Relationships between type of reaction and choice of reactor. Methods of obtaining and analyzing kinetic data. Relationship between mechanism and reaction rate and brief introduction to catalysis. Prereq: ECHE 360.

ECHE 365. Measurements Laboratory (3)
Laboratory introduction to measurement techniques in engineering. Matching measurements to approximate and exact physical models is stressed. Extraction of physical parameters and estimation of the errors in the parameter estimates is an important part of the course. Examples cover steady and unsteady state heat transfer, momentum transfer, and the first law of thermodynamics. Prereq: ECHE 360.

ECHE 367. Process Control (4)
Feedback control of chemical processes. The course involves extensive use of computer software and all exams are taken using the computer. Topics include: analysis of linear dynamical systems using Laplace transforms, derivation of unsteady state mathematical models of simple chemical processes, dynamic simulation of linear and nonlinear models, design of PID controllers by model inverse methods, tuning of controller to accommodate process model uncertainty, two degrees of freedom controllers, feed-forward and cascade control. Prereq: MATH 224.

ECHE 380. Electrochemical Technology (3)
Fundamentals of modern electrochemical technology and the engineering principles involved. Basics of classical electrochemistry; thermodynamics and kinetics. Engineering aspects of transport phenomena, scaling, and design as applied to electrochemical industries. Practical examples from metal finishing, batteries and fuel cells, and the electrolytic industries. Prereq: ECHE 260.

ECHE 381. Electrochemical Engineering (3)
Engineering aspects of electrochemical processes including current and potential distribution, mass transport and fluid mechanical effects. Examples from industrial processes including electroplating, industrial electrolysis, corrosion, and batteries. Prereq: ECHE 260 or permission of instructor. Cross-listed as ECHE 480.

ECHE 383. Chemical Engineering Applied to Microfabrication and Devices (3)
Silicon based microfabrication and micromachining require many chemical engineering technologies. Microfabricated devices such as sensors are also directly related to chemical engineering. The applications of chemical engineering principles to microfabrication and micromachining are introduced. Oxidation processing, chemical vapor deposition, etching and patterning techniques, electroplating and other technologies are discussed.

ECHE 398. Process Analysis and Design (3)
Economic analysis and cost estimation of chemical processes. Equipment and materials selection in the chemical process industry. Scale consideration, plant layout and plant site selection. Process analysis, heuristics and optimization. Environmental and plant safety issues. Prereq: ECHE 360, ECHE 361, ECHE 363, and ECHE 364.

ECHE 399. Chemical Engineering Design Project (3)
A capstone course for chemical engineering seniors. Uses material taught in previous and concurrent courses in an integrated fashion to solve chemical process design problems. Emphasis is placed on applying modern computer based design tools. Practicality, economics, scheduling, decision making with uncertainty, and proposal and report preparation. Numerous small exercises and one comprehensive process design project done by the class. Prereq: ECHE 398.

ECHE 400T. Graduate Teaching I (0)
All Ph.D. students are required to take this course. The experience includes elements from the following tasks: development of teaching or lecture materials, teaching recitation groups, providing laboratory assistance, tutoring, exam/quiz/homework preparation and grading, mentoring students. Prereq: Entering Ph.D. student in Chemical Engineering.

ECHE 401. Chemical Engineering Communications (1)
Introductory course in communication for Chemical Engineering graduate students: preparation of first proposal for thesis, preparation of technical reports and scientific papers, literature sources, reviewing proposals, and manuscripts for professional journals, and making effective technical presentations.

ECHE 460. Thermodynamics of Chemical Systems (3)
Phase equilibria, phase rule, chemical reaction equilibria in homogeneous and heterogeneous systems, ideal and non-ideal behavior of fluids and solutions, thermodynamic analysis of closed and open chemical systems with applications. Prereq: ECHE 363.

ECHE 461. Transport Phenomena (3)
Mechanisms of heat, mass, and momentum transport on both molecular and continuum basis. Generalized equations of transport. Techniques of solution for boundary value problems in systems of conduction, diffusion, and laminar flow. Boundary layer and turbulent systems. Prereq: ECHE 360.

ECHE 462. Chemical Reaction Engineering (3)
Steady and unsteady state mathematical modeling of chemical reactors from conservation principles. Interrelation of reaction kinetics, mass and heat transfer, flow phenomena. Catalytic and chemical vapor deposition reactors. Determination of kinetic parameters. Includes catalytic and chemical vapor deposition reactors. Prereq: ECHE 364.

ECHE 463. Techniques of Model-based Control (3)
Strategies of process control centered around the use of process models in the control system. Topics include single loop, feedforward, cascade and multivariable internal model control. Tuning controllers to accommodate process uncertainty. Treatment of control effort and output constraints in model predictive control and modular-multivariable control. Prereq: ECHE 367. Cross-listed as EECS 463.

ECHE 464. Surfaces and Adsorption (3)
Thermodynamics of interfaces, nature of interactions across phase boundaries, capillary wetting properties of adsorbed films, friction and lubrication, flotation, detergency, the surface of solids, relation of bulk to surface properties of materials, non-catalytic surface reaction. Prereq: CHEM 335 or equivalent.

ECHE 465. Catalysis (3)
Nature of catalytic processes, chemisorption, catalyst pore structure and surface area, role of lattice imperfections, geometric and electronic factors, dynamics and selectivity, typical reaction mechanisms, design of catalytic reactors.

ECHE 466. Colloid Science (3)
Stochastic processes and interparticle forces in colloidal dispersions. DLVO theory, stability criteria, and coagulation kinetics. Electrokinetic phenomena. Applications to electrophoresis, filtration, floatation, sedimentation, and suspension rheology. Investigation of suspensions, emulsions, gels, and association colloids. Prereq: CHEM 335 or equivalent.

ECHE 467. Statistical Theories of Materials (3)
The classic ensembles of statistical thermodynamics will be developed and used to compute molecular properties, properties of fluids, liquids and solids. Molecular dynamics for computing properties will be explained and illustrated. Monte Carlo techniques will be discussed. An introduction to the theory of transport coefficients will be given. Applications will include interfacial systems, polymer systems and electrochemical systems.

ECHE 469. Chemical Engineering Seminar (0)
Distinguished outside speakers present current research in various topics of chemical engineering science. Graduate students also present technical papers based on thesis research.

ECHE 474. Biotransport Processes
Biofluid dynamics in physiological and pathological systems. Heat and mass transfer in tissues and organs: energy metabolism and temperature regulation, oxygen and carbon dioxide transport. Cell and tissue engineering. Receptor-mediated processes: cell adhesion, proliferation and migration. Bio-MEMS: microfabrication methods in bioengineering.

ECHE 475. Chemical Engineering Analysis (3)
Mathematical analysis of problems in transport processes, chemical kinetics, and control systems. Examines vector spaces and matrices and their relation to differential transforms, series techniques (Fourier, Bessel functions, Legendre polynomials). Prereq: MATH 224.

ECHE 480. Electrochemical Engineering (3)
Engineering aspects of electrochemical processes including current and potential distribution, mass transport and fluid mechanical effects. Examples from industrial processes including electroplating, industrial electrolysis, corrosion, and batteries. Prereq: ECHE 260 or permission of instructor. Cross-listed as ECHE 381.

ECHE 483. Chemical Engineering Applied to Microfabrication and Devices (3)
Silicon based microfabrication and micromachining require many chemical engineering technologies. Microfabricated devices such as sensors are also directly related to chemical engineering. The applications of chemical engineering principles to microfabrication and micromachining are introduced. Oxidation processing, chemical vapor deposition, etching and patterning techniques, electroplating and other technologies are discussed. Graduate students will submit an additional final projection some technical aspect of microfabrication technology or devices. Prereq: ECHE 363 and ECHE 371.

ECHE 500T. Graduate Teaching II (0)
All Ph.D. students are required to take this course. The experience will include elements from the following tasks: development of teaching or lecture materials, teaching recitation groups, providing laboratory assistance, tutoring, exam/quiz/homework preparation and grading, mentoring students. Prereq: Ph.D. student in Chemical Engineering.

ECHE 560. Advanced Chemical Thermodynamics (3)
Chemical and phase equilibria in complex, multi-phase systems. Review of relevant theory. Sources of thermochemical data, methods of calculation and applications to phase diagrams, materials synthesis, electrochemistry, corrosion, water chemistry, silicon processing, chemical vapor deposition. Prereq: ECHE 460 or equivalent.

ECHE 561. Advanced Transport Phenomena (3)
(Extension of ECHE 461.) In-depth examination of methods of solving transport problems. Emphasis on coupled systems where two or more transport processes interact. Prereq: ECHE 461.

ECHE 575. Advanced Chemical Engineering Analysis (3)
Advanced analytical techniques for exact and approximate engineering analysis. Scale analysis and recursion techniques; asymptotic analysis of ordinary differential equations (regular and singular perturbations, WKB theory); approximation of integrals; method of characteristics, shocks; application to heat, mass and momentum transfer. Prereq: ECHE 475.

ECHE 600T. Graduate Teaching III (0)
All Ph.D. students are required to take this course. The experience will include elements from the following tasks: development of teaching or lecture materials, teaching recitation groups, providing laboratory assistance, tutoring, exam/quiz/homework preparation and grading, mentoring students. Prereq: Ph.D. student in Chemical Engineering.